The zoonotic emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and the ensuing coronavirus disease 2019 (COVID-19) pandemic have profoundly affected …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has killed millions of
people and continues to cause massive global upheaval. Coronaviruses are positive-strand …

SARS-CoV-2 is a betacoronavirus with a single-stranded, positive-sense, 30-kilobase RNA
genome responsible for the ongoing COVID-19 pandemic. Although population average …

Programmed ribosomal frameshifting is a key event during translation of the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA genome that allows synthesis of the …

SARS-CoV-2 is a betacoronavirus with a linear single-stranded, positive-sense RNA
genome, whose outbreak caused the ongoing COVID-19 pandemic. The ability of …

COVID-19 is the first known pandemic caused by a coronavirus, SARS-CoV-2, which is the
third virus in the family Coronaviridae to cause fatal infections in humans after SARS-CoV …

RNA molecules can fold into intricate shapes that can provide an additional layer of control
of gene expression beyond that of their sequence. In this Review, we discuss the current …

The multi-domain non-structural protein 3 (Nsp3) is the largest protein encoded by the
coronavirus (CoV) genome, with an average molecular mass of about 200 kD. Nsp3 is an …

Coronaviruses are pathogens with a serious impact on human and animal health. They
mostly cause enteric or respiratory disease, which can be severe and life threatening, eg, in …

The Coronaviridae is a family of positive-strand RNA viruses that includes SARS-CoV-2, the
etiologic agent of the COVID-19 pandemic. Bearing the largest single-stranded RNA …