Identification of biomarkers for the early detection of non-small cell lung cancer: a systematic review and meta-analysis

E Mohamed, DJ García Martínez, MS Hosseini… - …, 2024 - academic.oup.com
Lung cancer (LC) causes few symptoms in the earliest stages, leading to one of the highest
mortality rates among cancers. Low-dose computerised tomography (LDCT) is used to …

Development of autoantibody signatures for common cancers

M Kobayashi, H Katayama, JF Fahrmann… - Seminars in …, 2020 - Elsevier
A humoral immune response in the form of autoantibodies to tumor antigens occurs early
during tumor development. Identification of antigens that induce an autoantibody response …

An ingenious electrochemical aptasensor for detection of CYFRA 21–1 based on dual-output toehold mediated strand displacement reaction

J Liu, M Wang, C Zhang, G Li, Q Shen, L Zou - Bioelectrochemistry, 2022 - Elsevier
Abstract Herein, a “signal-on” electrochemical aptasensor based on dual-output toehold
mediated strand displacement reaction (TMSDR) was developed to detect cytokeratin …

Autoantibodies to tumor-associated antigens in lung cancer diagnosis

X Zhang, M Liu, X Zhang, Y Wang, L Dai - Advances in clinical chemistry, 2021 - Elsevier
Lung cancer (LC) accounts for the majority of cancer-related deaths worldwide. Although
screening the high-risk population by low-dose CT (LDCT) has reduced mortality, the cost …

Discovering panel of autoantibodies for early detection of lung cancer based on focused protein array

D Jiang, X Zhang, M Liu, Y Wang, T Wang… - Frontiers in …, 2021 - frontiersin.org
Substantial studies indicate that autoantibodies to tumor-associated antigens (TAAbs) arise
in early stage of lung cancer (LC). However, since single TAAbs as non-invasive biomarkers …

An abiotic fluorescent probe for the detection and quantification of carcinoembryonic antigen

JS Lee, IH Song, SD Warkad, GS Yeom, SB Nimse - Bioorganic Chemistry, 2022 - Elsevier
The reported methods mainly use biomolecules such as antibodies, enzymes, and aptamers
for biomarker detection. However, applying an abiotic fluorescent probe to detect cancer …

A split-type photoelectrochemical immunosensing platform based on atom-efficient cation exchange for physiological monitoring

X Wang, D Leng, F Li, L Liu, X Ren, JY Lee, H Ju… - Analytica Chimica …, 2023 - Elsevier
Ultrasensitive and accurate physiological monitoring is of great significance for disease
diagnosis and treatment. In this project, an efficient photoelectrochemical (PEC) split-type …

[HTML][HTML] Enhanced Lung Cancer Detection Using a Combined Ratio of Antigen–Autoantibody Immune Complexes against CYFRA 21-1 and p53

H Kim, JK Lee, HR Kim, YJ Hong - Cancers, 2024 - mdpi.com
Simple Summary This study investigated a new blood test (9G testTM Cancer/Lung) for early
lung cancer detection. This test measures complexes of autoantibodies with specific lung …

Self-powered biosensor for specifically detecting creatinine in real time based on the piezo-enzymatic-reaction effect of enzyme-modified ZnO nanowires

M Wang, G Zi, J Liu, Y Song, X Zhao, Q Wang, T Zhao - Biosensors, 2021 - mdpi.com
Creatinine has become an important indicator for the early detection of uremia. However,
due to the disadvantages of external power supply and large volume, some commercial …

Ultrasensitive label-free detection for lung cancer CYFRA 21-1 DNA based on ring-opening polymerization

X Li, Y Zhang, L Hao, Y Liu, X Wang, H Yang, J Kong - Talanta, 2021 - Elsevier
Abstract Cytokeratin fragment antigen 21-1 (CYFRA 21-1) DNA is perceived as sensitive
tumor marker for the diagnosis of non-small cell lung cancer and other tumor. Herein, linear …