Quantification of Residual Water in Pharmaceutical Frozen Solutions via 1H Solid-state NMR
Freezing is essential for the stability of biological drug substances and products, particularly
in frozen solution formulations and during the primary drying of lyophilized preparations …
in frozen solution formulations and during the primary drying of lyophilized preparations …
[HTML][HTML] Enabling efficient design of biological formulations through advanced characterizations
K Chen, JK Cheung, HY Kim, A Leone, K Mallela… - Pharmaceutical …, 2023 - Springer
Biologics continue to play an increasingly dominant role in the modern pharmaceutical
market. The primary objective of formulation development is to efficiently deliver a …
market. The primary objective of formulation development is to efficiently deliver a …
Machine Learning for Analysis of Structural Characterization
A Jayaraman, S Lu - The Digital Transformation of Product …, 2024 - taylorfrancis.com
For characterization of structure within formulations, researchers often use one or more of
these techniques–microscopy, spectroscopy, and scattering. AI can be used in many …
these techniques–microscopy, spectroscopy, and scattering. AI can be used in many …
Molecular Mechanisms for Stabilizing Biologics in the Solid State
Protein drugs exhibit challenges of biophysical and biochemical instability due to their
structural complexity and rich dynamics. Solid-state biologics aim to enhance stability by …
structural complexity and rich dynamics. Solid-state biologics aim to enhance stability by …