Practical considerations in medical cannabis administration and dosing

CA MacCallum, EB Russo - European journal of internal medicine, 2018 - Elsevier
Cannabis has been employed medicinally throughout history, but its recent legal prohibition,
biochemical complexity and variability, quality control issues, previous dearth of …

Routes of administration for cannabis use–basic prevalence and related health outcomes: A scoping review and synthesis

C Russell, S Rueda, R Room, M Tyndall… - International Journal of …, 2018 - Elsevier
Background Cannabis use is common, and associated with adverse health
outcomes.'Routes of administration'(ROAs) for cannabis use have increasingly diversified, in …

Taming THC: potential cannabis synergy and phytocannabinoid‐terpenoid entourage effects

EB Russo - British journal of pharmacology, 2011 - Wiley Online Library
Tetrahydrocannabinol (THC) has been the primary focus of cannabis research since 1964,
when Raphael Mechoulam isolated and synthesized it. More recently, the synergistic …

Cannabidiol (CBD) use in psychiatric disorders: A systematic review

S Bonaccorso, A Ricciardi, C Zangani, S Chiappini… - Neurotoxicology, 2019 - Elsevier
Abstract Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) are the most represented
phytocannabinoids in Cannabis sativa plants. However, CBD may present with a different …

Cannabinoid dose and label accuracy in edible medical cannabis products

R Vandrey, JC Raber, ME Raber, B Douglass, C Miller… - Jama, 2015 - jamanetwork.com
Methods| An Internet directory of dispensaries, with a menu of products available at each,
was used to determine purchase locations in San Francisco, California, Los Angeles …

Comprehensive review of medicinal marijuana, cannabinoids, and therapeutic implications in medicine and headache: what a long strange trip it's been…

EP Baron - Headache: The Journal of Head and Face Pain, 2015 - Wiley Online Library
Background The use of cannabis, or marijuana, for medicinal purposes is deeply rooted
though history, dating back to ancient times. It once held a prominent position in the history …

[HTML][HTML] Tasty THC: promises and challenges of cannabis edibles

DG Barrus, KL Capogrossi, SC Cates… - Methods report (RTI …, 2016 - ncbi.nlm.nih.gov
Food products containing cannabis extract (edibles) have emerged as a popular and
lucrative facet of the legalized market for both recreational and medicinal cannabis. The …

Pharmacokinetic profile of oral cannabis in humans: blood and oral fluid disposition and relation to pharmacodynamic outcomes

R Vandrey, ES Herrmann, JM Mitchell… - Journal of analytical …, 2017 - academic.oup.com
Most research on cannabis pharmacokinetics has evaluated inhaled cannabis, but oral
(“edible”) preparations comprise an increasing segment of the cannabis market. To assess …

Acute effects of a single, oral dose of d9-tetrahydrocannabinol (THC) and cannabidiol (CBD) administration in healthy volunteers

R Martin-Santos, J a Crippa, A Batalla… - Current …, 2012 - ingentaconnect.com
Rationale: Animal and humans studies suggest that the two main constituents of cannabis
sativa, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) have quite different acute …

The why behind the high: determinants of neurocognition during acute cannabis exposure

JG Ramaekers, NL Mason, L Kloft… - Nature Reviews …, 2021 - nature.com
Acute cannabis intoxication may induce neurocognitive impairment and is a possible cause
of human error, injury and psychological distress. One of the major concerns raised about …