Type 1 diabetes mellitus (T1DM) is a chronic metabolic disease characterized by
autoimmune destruction of pancreatic β cells. Transplantation of immunoisolated pancreatic …

Oxygen (O2) generating biomaterials are emerging as important compositions to improve
our capabilities in supporting tissue engineering and regenerative therapeutics. Several in …

Intrahepatic islet transplantation is the standard cell therapy for β cell replacement. However,
the shortage of organ donors and an unsatisfactory engraftment limit its application to a …

Manufacturing macroscale cell-laden architectures is one of the biggest challenges faced
nowadays in the domain of tissue engineering. Such living constructs, in fact, pose strict …

Effective methods to alleviate hypoxia are necessary for the proper healing of chronic
wounds. However, current oxygen (O 2) delivery methods suffer from limitations, such as low …

Novel transplantation techniques are currently under development to preserve the function
of impaired tissues or organs. While current technologies can enhance the survival of …

Human allogeneic islet transplantation (ITx) is emerging as a promising treatment option for
qualified patients with type 1 diabetes. However, widespread clinical application of …

A new concept, assembling cell‐laden tissue modules, is for the first time proposed for soft
tissue engineering. Adipose‐vascular tissue modules composed of a synthetic polymer …

Pancreatic islets transplantation is an optimal alternative to exogenous insulin injection for
long-term effective type 1 diabetes treatment. However, direct islets transplantation without …

Highlights•Islet encapsulation strategies are classified based on islet-to-host
distance.•Material design, cell biology and immunology determine encapsulation success.• …