There is increasing evidence both in humans and rodents linking the endogenous estrogen
17β-estradiol (E2) to the maintenance of glucose homeostasis. Postmenopausal women …

Protecting the functional mass of insulin-producing β cells of the pancreas is a major
therapeutic challenge in patients with type 1 (T1DM) or type 2 diabetes mellitus (T2DM). The …

Obesity in women of reproductive age has a number of adverse metabolic effects, including
Type II Diabetes (T2D), dyslipidemia, and cardiovascular disease. It is associated with …

Context: In postmenopausal women, endogenous estradiol (E2) and free testosterone (T)
have been positively associated with glucose intolerance and type 2 diabetes. Most studies …

In this study, we used ob/ob mice as a model to investigate the effects of long-term estradiol
administration on insulin sensitivity and to explore the mechanisms that underlie the …

Background. The prevalence of the metabolic syndrome increases with age and after the
onset of menopause, and may explain in part the apparent acceleration of cardiovascular …

The purpose of this study was to test whether the insulin sensitivity, lipid metabolism and the
susceptibility of the heart to ischemia/reperfusion injury are modulated by the chronic …

Context Some women living with type 1 diabetes complain of changes in glucose values
according to the different phases of menstruation. Objective To evaluate this variability …

Sex differences and the role of gonadal hormones in modulating insulin sensitivity and
glucose tolerance are of increasing interest and importance because of the increasing …

The estrogen receptor α-selective agonist propyl pyrazole triol improves glucose tolerance in
ob/ob mice: potential molecular mechanisms in: Journal of Endocrinology Volume 243 Issue 2 …