Determinants of genetic diversity

H Ellegren, N Galtier - Nature Reviews Genetics, 2016 - nature.com
Genetic polymorphism varies among species and within genomes, and has important
implications for the evolution and conservation of species. The determinants of this variation …

Genomic signatures of selection at linked sites: unifying the disparity among species

AD Cutter, BA Payseur - Nature Reviews Genetics, 2013 - nature.com
Population genetics theory supplies powerful predictions about how natural selection
interacts with genetic linkage to sculpt the genomic landscape of nucleotide polymorphism …

[图书][B] Ecological speciation

P Nosil - 2012 - books.google.com
The origin of biological diversity, via the formation of new species, can be inextricably linked
to adaptation to the ecological environment. Specifically, ecological processes are central to …

The Many Landscapes of Recombination in Drosophila melanogaster

JM Comeron, R Ratnappan, S Bailin - 2012 - journals.plos.org
Recombination is a fundamental biological process with profound evolutionary implications.
Theory predicts that recombination increases the effectiveness of selection in natural …

Natural selection constrains neutral diversity across a wide range of species

RB Corbett-Detig, DL Hartl, TB Sackton - PLoS biology, 2015 - journals.plos.org
The neutral theory of molecular evolution predicts that the amount of neutral polymorphisms
within a species will increase proportionally with the census population size (Nc). However …

The effects of deleterious mutations on evolution at linked sites

B Charlesworth - Genetics, 2012 - academic.oup.com
The process of evolution at a given site in the genome can be influenced by the action of
selection at other sites, especially when these are closely linked to it. Such selection …

Adaptive evolution: evaluating empirical support for theoretical predictions

CF Olson-Manning, MR Wagner… - Nature Reviews …, 2012 - nature.com
Adaptive evolution is shaped by the interaction of population genetics, natural selection and
underlying network and biochemical constraints. Variation created by mutation, the raw …

Selection at Linked Sites Shapes Heritable Phenotypic Variation in C. elegans

MV Rockman, SS Skrovanek, L Kruglyak - Science, 2010 - science.org
Mutation generates the heritable variation that genetic drift and natural selection shape. In
classical quantitative genetic models, drift is a function of the effective population size and …

Old trade, new tricks: insights into the spontaneous mutation process from the partnering of classical mutation accumulation experiments with high-throughput …

V Katju, U Bergthorsson - Genome Biology and Evolution, 2019 - academic.oup.com
Mutations spawn genetic variation which, in turn, fuels evolution. Hence, experimental
investigations into the rate and fitness effects of spontaneous mutations are central to the …

Estimating the genome-wide contribution of selection to temporal allele frequency change

V Buffalo, G Coop - … of the National Academy of Sciences, 2020 - National Acad Sciences
Rapid phenotypic adaptation is often observed in natural populations and selection
experiments. However, detecting the genome-wide impact of this selection is difficult since …