Podosomes and invadopodia are actin-based dynamic protrusions of the plasma membrane
of metazoan cells that represent sites of attachment to—and degradation of—the …

Proteolytic enzymes belonging to the A Disintegin And Metalloproteinase (ADAM) family are
able to cleave transmembrane proteins close to the cell surface, in a process referred to as …

The neural crest is a vertebrate-specific migratory stem cell population that generates a
remarkably diverse set of cell types and structures. Because many of the morphological …

Collective cell migration is the coordinated movement emerging from the interaction of at
least two cells. In multicellular organisms, collective cell migration is ubiquitous. During …

In the adult organism, cell migration is required for physiological processes such as
angiogenesis and immune surveillance, as well as pathological events such as tumor …

The cephalic neural crest (NC) cells delaminate from the neuroepithelium in large numbers
and undergo collective cell migration under the influence of multiple factors including …

Neural crest cells are highly migratory cells that give rise to many derivatives including
peripheral ganglia, craniofacial structures and melanocytes. Neural crest cells migrate along …

Our increasing comprehension of neural crest cell development has reciprocally advanced
our understanding of cadherin expression, regulation, and function. As a transient …

Cell migration is critical for proper development of the embryo and is also used by many cell
types to perform their physiological function. For instance, cell migration is essential for …

Since the time of Darwin, biologists have sought to understand the origins and maintenance
of life's diversity of form. However, the nature of the exact DNA mutations and molecular …