Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

Candida–bacterial cross-kingdom interactions

KR Eichelberger, S Paul, BM Peters, JE Cassat - Trends in Microbiology, 2023 - cell.com
While the fungus Candida albicans is a common colonizer of healthy humans, it is also
responsible for mucosal infections and severe invasive disease. Understanding the …

Longdan Xiegan decoction ameliorates vulvovaginal candidiasis by inhibiting the NLRP3 inflammasome via the Toll-like receptor/MyD88 pathway

X Feng, H Zhang, K Hu, G Shi, D Wu, J Shao… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Longdan Xiegan decoction (LXD) is a
standardized herbal prescription originally documented in the “Medical Formula Collection” …

[HTML][HTML] “Under Pressure”–How fungi evade, exploit, and modulate cells of the innate immune system

T Lange, L Kasper, MS Gresnigt, S Brunke… - Seminars in Immunology, 2023 - Elsevier
The human immune system uses an arsenal of effector mechanisms to prevent and
counteract infections. Yet, some fungal species are extremely successful as human …

Inflammatory cytokine signalling in vulvovaginal candidiasis: a hot mess driving immunopathology

KO Cheng, DE Montano, T Zelante… - Oxford Open …, 2024 - academic.oup.com
Protective immunity to opportunistic fungal infections consists of tightly regulated innate and
adaptive immune responses that clear the infection. Immune responses to infections of the …

A New Phenotype in Candida-Epithelial Cell Interaction Distinguishes Colonization- versus Vulvovaginal Candidiasis-Associated Strains

A Sala, A Ardizzoni, L Spaggiari, N Vaidya… - MBio, 2023 - Am Soc Microbiol
Vulvovaginal candidiasis (VVC) affects nearly 3/4 of women during their lifetime, and its
symptoms seriously reduce quality of life. Although Candida albicans is a common …

Molecular association of Candida albicans and vulvovaginal candidiasis: focusing on a solution

H David, AP Solomon - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
Candida albicans-mediated vulvovaginal candidiasis (VVC) is a significant challenge in
clinical settings, owing to the inefficacy of current antifungals in modulating virulence …

Vulvovaginal candidiasis in postmenopausal women

M Becker, R Sobel - Current Infectious Disease Reports, 2023 - Springer
Abstract Purpose of Review Vulvovaginal candidiasis (VVC) is one of the most common
vaginal infections worldwide, but limited evidence-based data is available on …

Microbial adaptive pathogenicity strategies to the host inflammatory environment

SUJ Hitzler, C Fernández, DE Montaño… - FEMS Microbiology …, 2024 - academic.oup.com
Pathogenic microorganisms can infect a variety of niches in the human body. During
infection, microbes can only persist if they adapt adequately to the dynamic host …

Ethinylestradiol in combined hormonal contraceptive has a broader effect on serum proteome compared with estradiol valerate: a randomized controlled trial

MH Kangasniemi, RK Arffman, S Joenväärä… - Human …, 2023 - academic.oup.com
STUDY QUESTION Does an estradiol-based combined oral contraceptive (COC) have a
milder effect on the serum proteome than an ethinylestradiol (EE)-based COC or dienogest …