Adjuvants are vaccine components that enhance the magnitude, breadth and durability of
the immune response. Following its introduction in the 1920s, alum remained the only …

Vaccinations are one of the most important preventive tools against infectious diseases.
Over time, many different types of vaccines have been developed concerning the antigen …

Modern subunit vaccines based on homogeneous antigens offer more precise targeting and
improved safety compared with traditional whole-pathogen vaccines. However, they are also …

In the present scenario, immunization is of utmost importance as it keeps us safe and
protects us from infectious agents. Despite the great success in the field of vaccinology …

After decades of slow progress, the last years have seen a rapid acceleration of the
development of adjuvanted vaccines which have lately been approved for human use …

Saponins are potent and safe vaccine adjuvants, but their mechanisms of action remain
incompletely understood. Here, we explored the properties of several saponin formulations …

Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …

Vaccination was first pioneered in the 18th century by Edward Jenner and eventually led to
the development of the smallpox vaccine and subsequently the eradication of smallpox. The …

Vaccines are one of the most powerful technologies supporting public health. The adaptive
immune response induced by immunization arises following appropriate activation and …

With the rapid development of nanotechnology as well as growing interest in
immunotherapy, a great number of vaccine delivery vehicles have been explored in order to …