Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics
Y Duan, K Gong, S Xu, F Zhang, X Meng… - Signal Transduction and …, 2022 - nature.com
Disturbed cholesterol homeostasis plays critical roles in the development of multiple
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and …
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and …
Protease targeted COVID-19 drug discovery and its challenges: Insight into viral main protease (Mpro) and papain-like protease (PLpro) inhibitors
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) brutally perils physical and
mental health worldwide. Unavailability of effective anti-viral drug rendering global threat of …
mental health worldwide. Unavailability of effective anti-viral drug rendering global threat of …
Cytokine storm in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic approaches: the REPROGRAM consortium position paper
Cytokine storm is an acute hyperinflammatory response that may be responsible for critical
illness in many conditions including viral infections, cancer, sepsis, and multi-organ failure …
illness in many conditions including viral infections, cancer, sepsis, and multi-organ failure …
In-hospital use of statins is associated with a reduced risk of mortality among individuals with COVID-19
Statins are lipid-lowering therapeutics with favorable anti-inflammatory profiles and have
been proposed as an adjunct therapy for COVID-19. However, statins may increase the risk …
been proposed as an adjunct therapy for COVID-19. However, statins may increase the risk …
Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19
A Gupta, MV Madhavan, TJ Poterucha… - Nature …, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) can result in a hyperinflammatory state,
leading to acute respiratory distress syndrome (ARDS), myocardial injury, and thrombotic …
leading to acute respiratory distress syndrome (ARDS), myocardial injury, and thrombotic …
[HTML][HTML] PoLA/CFPiP/PCS/PSLD/PSD/PSH guidelines on diagnosis and therapy of lipid disorders in Poland 2021
M Banach, P Burchardt, K Chlebus… - Archives of Medical …, 2021 - ncbi.nlm.nih.gov
Moreover, over the last few years the approach to treatment of patients with a high
cardiovascular risk has totally changed from treatment aimed at a specific risk factor (ie …
cardiovascular risk has totally changed from treatment aimed at a specific risk factor (ie …
[HTML][HTML] Relation of statin use prior to admission to severity and recovery among COVID-19 inpatients
The impact of statins, angiotensin-converting enzyme inhibitors and angiotensin II receptor
blockers (ARBs) on coronavirus disease 2019 (COVID-19) severity and recovery is …
blockers (ARBs) on coronavirus disease 2019 (COVID-19) severity and recovery is …
The effects of ARBs, ACEis, and statins on clinical outcomes of COVID-19 infection among nursing home residents
Objectives Angiotensin-converting enzyme inhibitors (ACEi), angiotensin II receptor blockers
(ARBs), and HMG-CoA reductase inhibitors (“statins”) have been hypothesized to affect …
(ARBs), and HMG-CoA reductase inhibitors (“statins”) have been hypothesized to affect …
Effect of Statins on Serum level of hs‐CRP and CRP in Patients with Cardiovascular Diseases: A Systematic Review and Meta‐Analysis of Randomized Controlled …
T Kandelouei, M Abbasifard, D Imani… - Mediators of …, 2022 - Wiley Online Library
Background. Several studies have reported that statins have anti‐inflammatory effects.
Nevertheless, results of clinical trials concerning the effect of statins on the levels of C …
Nevertheless, results of clinical trials concerning the effect of statins on the levels of C …
Cholesterol in relation to COVID-19: should we care about it?
Current data suggest that infection with severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) causing corona virus disease-19 (COVID-19) seems to follow a more severe …
(SARS-CoV-2) causing corona virus disease-19 (COVID-19) seems to follow a more severe …