Machine learning and deep learning applications in microbiome research

R Hernández Medina, S Kutuzova… - ISME …, 2022 - academic.oup.com
The many microbial communities around us form interactive and dynamic ecosystems called
microbiomes. Though concealed from the naked eye, microbiomes govern and influence …

The role of the probiotic Akkermansia muciniphila in brain functions: insights underpinning therapeutic potential

R Xu, Y Zhang, S Chen, Y Zeng, X Fu… - Critical reviews in …, 2023 - Taylor & Francis
The role of Akkermansia muciniphila, one of the most abundant microorganisms of the
intestinal microbiota, has been studied extensively in metabolic diseases, such as obesity …

[HTML][HTML] Host genetic regulation of human gut microbial structural variation

DV Zhernakova, D Wang, L Liu, S Andreu-Sánchez… - Nature, 2024 - nature.com
Although the impact of host genetics on gut microbial diversity and the abundance of specific
taxa is well established,,,,–, little is known about how host genetics regulates the genetic …

Co-diversification of an intestinal Mycoplasma and its salmonid host

JA Rasmussen, P Kiilerich, AS Madhun… - The ISME …, 2023 - academic.oup.com
Understanding the evolutionary relationships between a host and its intestinal resident
bacteria can transform how we understand adaptive phenotypic traits. The interplay between …

The gastrointestinal microbiome in dairy cattle is constrained by the deterministic driver of the region and the modified effect of diet

L Lin, Z Lai, J Zhang, W Zhu, S Mao - Microbiome, 2023 - Springer
Abstract Background Dairy cattle (Bos taurus), especially Holstein cows, which are the
highest-producing dairy animals and are widely bred to provide milk products to humans …

Microbiome breeding: conceptual and practical issues

UG Mueller, TA Linksvayer - Trends in microbiology, 2022 - cell.com
Microbiome breeding is a new artificial selection technique that seeks to change the genetic
composition of microbiomes in order to benefit plant or animal hosts. Recent experimental …

Uncovering the genomic basis of an extraordinary plant invasion

VC Bieker, P Battlay, B Petersen, X Sun, J Wilson… - Science …, 2022 - science.org
Invasive species are a key driver of the global biodiversity crisis, but the drivers of
invasiveness, including the role of pathogens, remain debated. We investigated the genomic …

Amino acid utilization allows intestinal dominance of Lactobacillus amylovorus

Y Jing, C Mu, H Wang, J Shen, EG Zoetendal… - The ISME …, 2022 - academic.oup.com
The mammalian intestine harbors heterogeneous distribution of microbes among which
specific taxa (eg Lactobacillus) dominate across mammals. Deterministic factors such as …

Strategies for breeding crops for future environments

J Salse, RL Barnard, C Veneault-Fourrey… - Trends in Plant …, 2023 - cell.com
The green revolution successfully increased agricultural output in the early 1960s by relying
primarily on three pillars: plant breeding, irrigation, and chemical fertilization. Today, the …

Field and laboratory guidelines for reliable bioinformatic and statistical analysis of bacterial shotgun metagenomic data

O Aizpurua, RR Dunn, LH Hansen… - Critical Reviews in …, 2024 - Taylor & Francis
Shotgun metagenomics is an increasingly cost-effective approach for profiling
environmental and host-associated microbial communities. However, due to the complexity …