[HTML][HTML] Adaptive optics imaging of the human retina

SA Burns, AE Elsner, KA Sapoznik, RL Warner… - Progress in retinal and …, 2019 - Elsevier
Adaptive Optics (AO) retinal imaging has provided revolutionary tools to scientists and
clinicians for studying retinal structure and function in the living eye. From animal models to …

Promises and pitfalls of evaluating photoreceptor-based retinal disease with adaptive optics scanning light ophthalmoscopy (AOSLO)

N Wynne, J Carroll, JL Duncan - Progress in retinal and eye research, 2021 - Elsevier
Adaptive optics scanning light ophthalmoscopy (AOSLO) allows visualization of the living
human retina with exquisite single-cell resolution. This technology has improved our …

Adaptive optics reveals photoreceptor abnormalities in diabetic macular ischemia

PL Nesper, F Scarinci, AA Fawzi - PLoS One, 2017 - journals.plos.org
Diabetic macular ischemia (DMI) is a phenotype of diabetic retinopathy (DR) associated with
chronic hypoxia of retinal tissue. The goal of this prospective observational study was to …

Distribution of cone density, spacing and arrangement in adult healthy retinas with adaptive optics flood illumination

R Legras, A Gaudric, K Woog - PloS one, 2018 - journals.plos.org
The aim of this article is to analyse cone density, spacing and arrangement using an
adaptive optics flood illumination retina camera (rtx1™) on a healthy population. Cone …

Biofeedback fixation training method for improving eccentric vision in patients with loss of foveal function secondary to different maculopathies

MU Morales, S Saker, C Wilde, M Rubinstein… - International …, 2020 - Springer
Purpose Fixation stability (FS) of the preferred retinal locus (PRL) may be improved by
biofeedback fixation training (BFT) with microperimetry. Such training can be done on the …

Photoreceptor-based biomarkers in AOSLO retinal imaging

KM Litts, RF Cooper, JL Duncan… - … ophthalmology & visual …, 2017 - iovs.arvojournals.org
Improved understanding of the mechanisms underlying inherited retinal degenerations has
created the possibility of developing much needed treatments for these relentless, blinding …

Cellular imaging of inherited retinal diseases using adaptive optics

JS Gill, M Moosajee, AM Dubis - Eye, 2019 - nature.com
Adaptive optics (AO) is an insightful tool that has been increasingly applied to existing
imaging systems for viewing the retina at a cellular level. By correcting for individual optical …

Adaptive optics imaging of parafoveal cones in type 1 diabetes

M Lombardo, M Parravano, G Lombardo, M Varano… - Retina, 2014 - journals.lww.com
Purpose: To evaluate the parafoveal cone density in patients with Type 1 diabetes mellitus
(DM1). Methods: Adaptive optics retinal images of the photoreceptor mosaic were acquired …

Extracting spacing-derived estimates of rod density in healthy retinae

H Heitkotter, EJ Patterson, EN Woertz… - Biomedical Optics …, 2022 - opg.optica.org
Quantification of the rod photoreceptor mosaic using adaptive optics scanning light
ophthalmoscopy (AOSLO) remains challenging. Here we demonstrate a method for deriving …

Advances in understanding the molecular basis of the first steps in color vision

L Hofmann, K Palczewski - Progress in retinal and eye research, 2015 - Elsevier
Serving as one of our primary environmental inputs, vision is the most sophisticated sensory
system in humans. Here, we present recent findings derived from energetics, genetics and …