The role of lipids in the regulation of immune responses

C Garcia, CJ Andersen, CN Blesso - Nutrients, 2023 - mdpi.com
Lipid metabolism plays a major role in the regulation of the immune system. Exogenous
(dietary and microbial-derived) and endogenous (non-microbial-derived) lipids play a direct …

Lipids and the hallmarks of ageing: from pathology to interventions

R Sharma, B Diwan - Mechanisms of Ageing and Development, 2023 - Elsevier
Lipids are critical structural and functional architects of cellular homeostasis. Change in
systemic lipid profile is a clinical indicator of underlying metabolic pathologies, and …

[HTML][HTML] MSTN mutant promotes myogenic differentiation by increasing demethylase TET1 expression via the SMAD2/SMAD3 pathway

L Gao, M Yang, Z Wei, M Gu, L Yang… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Myostatin (MSTN) is mostly expressed in skeletal muscle and plays crucial roles in the
negative regulation of muscle mass development. The methylation and demethylation of …

Avobenzone-loaded and omega-3-enriched lipid formulations for production of UV blocking sunscreen gels and textiles

AR Caldas, MJ Faria, A Ribeiro, R Machado… - Journal of Molecular …, 2021 - Elsevier
Given the growing harmful effects of ultraviolet (UV) radiation there is an urgent need to
develop effective strategies to prevent skin damages. Therefore, hydrogel or cotton and wool …

[HTML][HTML] Diet impacts on gene expression in healthy colon tissue: Insights from the BarcUVa-Seq study

M Obón-Santacana, F Moratalla-Navarro, E Guinó… - Nutrients, 2024 - pmc.ncbi.nlm.nih.gov
(1) Introduction: The global rise of gastrointestinal diseases, including colorectal cancer and
inflammatory bowel diseases, highlights the need to understand their causes. Diet is a …

[HTML][HTML] DHA sensor GPR120 in host defense exhibits the dual characteristics of regulating dendritic cell function and skewing the balance of Th17/Tregs

C Zhao, J Zhou, Y Meng, N Shi, X Wang… - … Journal of Biological …, 2020 - ncbi.nlm.nih.gov
In addition to functioning as an antioxidant, anti-inflammatory and age-defying cellular
component, DHA impacts the immune system by facilitating the pathogen invasion. The …

Maternal fatty acid intake and human embryonic growth: the Rotterdam Periconception Cohort

E Rubini, L van Rossem, S Schoenmakers… - European Journal of …, 2024 - Springer
The required intake of macronutrients by women during the periconceptional period for
optimal fetal growth is the subject of ongoing investigation. Intake of polyunsaturated fatty …

[HTML][HTML] RNA-Seq Analysis of Pubertal Mammary Epithelial Cells Reveals Novel n-3 Polyunsaturated Fatty Acid Transcriptomic Changes in the fat-1 Mouse Model

CDC Buchanan, R Ashraf, LM Hillyer, W Tu, JX Kang… - Nutrients, 2024 - mdpi.com
Background: The early exposure of nutrients during pubertal mammary gland development
may reduce the risk of developing breast cancer later in life. Anticancer n-3 polyunsaturated …

Cellular Basis of Adjuvant Role of n-3 Polyunsaturated Fatty Acids in Cancer Therapy: Molecular Insights and Therapeutic Potential against Human Melanoma

C Rojas-Solé, B Torres-Herrera, S Gelerstein-Claro… - Applied Sciences, 2024 - mdpi.com
Human melanoma is a highly aggressive malignant tumor originating from epidermal
melanocytes, characterized by intrinsic resistance to apoptosis and the reprogramming of …

[HTML][HTML] Generation of Codon-Optimized Fad3 Gene Transgenic Bovine That Produce More n-3 Polyunsaturated Fatty Acids

G Su, Z Wei, C Bai, D Li, X Zhao, X Liu, L Song… - Animals, 2025 - mdpi.com
Polyunsaturated fatty acids (PUFAs) such as linoleic acid (18: 2, n-6) and α-linolenic acid
(18: 3, n-3) are essential for the growth, development, and well-being of mammals. However …