Smoking a cigarette generates over 4000 chemicals that have a deleterious impact on each
part of the human body. It produces three main severe effects on the liver organ: oncogenic …

Background Based on randomized controlled trials, a network meta-analysis was conducted
to compare treatment effects across varenicline and related smoking interventions. Methods …

Neurodegenerative diseases (NDDs) and neuropsychiatric disorders (NPDs) are two
common causes of death in elderly people, which includes progressive neuronal cell death …

Electronic nicotine delivery systems (ENDS), which are becoming increasingly popular in
many parts of the world, have recently become more sophisticated in terms of their more …

Nicotine addiction and dependence is a chronic relapsing disease driven by addiction to
nicotine. Proactive treatment for all tobacco users, regardless of their readiness to quit, is …

Objectives To identify triggers of acute mood episodes in bipolar disorder (BD). Methods We
performed a systematic review in the following databases: Pubmed, Embase, and PsycInfo …

Abstract Background/Objectives Weight gain is a barrier to smoking cessation. Previous
interventions targeting weight gain while quitting smoking have largely been unsuccessful …

Background Adhering to varenicline has been shown to significantly improve the chances of
successfully quitting smoking, with studies indicating a twofold increase in 6-month quit …

Nicotinic acetylcholine receptor (nAChR) α6 subunit RNA expression is relatively restricted
to midbrain regions and is located presynaptically on dopaminergic neurons projecting to …

Acetylcholine signaling is attenuated in early Alzheimer's disease (AD) and other dementias.
A significant reduction in the expression of nicotinic acetylcholine receptors (nAChRs) in the …