Cancer is often characterised by the presence of hypoxia and inflammation. Paramount to
the mechanisms controlling cellular responses under such stress stimuli, are the …

The occurrence of cancer entails a series of genetic mutations that favor uncontrollable
tumor growth. It is believed that various factors collectively contribute to cancer, and there is …

The molecular bases of how host genetic variation impacts the gut microbiome remain
largely unknown. Here we used a genetically diverse mouse population and applied …

Although therapeutic targets have been developed for colorectal cancer (CRC) therapy, the
therapeutic effects are not ideal and the survival rate for CRC patients remains poor …

Background JMJD8 has recently been identified as a cancer-related gene, but current
studies provide limited information. We aimed to clarify its roles and the potential …

Spatial cognition is used by most organisms to navigate their environment. Some species
rely particularly heavily on specialized spatial cognition to survive, suggesting that a …

Atherosclerosis is a chronic inflammatory disease, and the increased expression of
adhesion molecules on vascular smooth muscle cells contributes to the progression of …

The STING-mediated type I interferon (IFN) signaling pathway has been shown to play
critical roles in antitumor immunity. Here, we demonstrate that an endoplasmic reticulum …

Jumonji C domain-containing (JMJD) proteins are mostly epigenetic regulators that
demethylate histones. However, a hitherto neglected subfamily of JMJD proteins …

Heat stress negatively affects health and production in cows. Examining the cellular
response to heat stress could reveal underlying protective molecular mechanisms …