Pharmacological activity and mechanism of pyrazines

W Hou, W Dai, H Huang, SL Liu, J Liu, LJ Huang… - European Journal of …, 2023 - Elsevier
Heterocycles are common in the structure of drugs used clinically to deal with diseases.
Such drugs usually contain nitrogen, oxygen and sulfur, which possess electron-accepting …

[HTML][HTML] Quinoxaline derivatives: Recent discoveries and development strategies towards anticancer agents

V Montero, M Montana, M Carré, P Vanelle - European Journal of …, 2024 - Elsevier
Cancer is a leading cause of death and a major health problem worldwide. While many
effective anticancer agents are available, most drugs currently on the market are not specific …

[HTML][HTML] Probing the anticancer activities of facial trioxorhenium and tricarbonylrhenium compounds with heterocyclic ligands

C Davison, S Abdullah, CJ Smit, P Dlamini… - Chemico-Biological …, 2025 - Elsevier
The cytotoxicity of four rhenium compounds: fac-[ReO 3 (impy) CH 3](1)(impy= 2-(1H-
imidazole-2-yl) pyridine), fac-[Re (CO) 3 (bzimpy) Cl](2)(bzimpy= 2-(2-pyridyl) …

[HTML][HTML] Advances in Cholinesterase Inhibitor Research—An Overview of Preclinical Studies of Selected Organoruthenium (II) Complexes

MC Žužek - International journal of molecular sciences, 2024 - mdpi.com
Cholinesterase (ChE) inhibitors are crucial therapeutic agents for the symptomatic treatment
of certain chronic neurodegenerative diseases linked to functional disorders of the …

Synthesis, crystal structure, and PTPs inhibition activity of a {N, S}-coordinated paddle wheel platinum(II) complex

S Wu, S Li, X Liu, YB Wu, L Lu, C Yuan - Transition Metal Chemistry, 2023 - Springer
A dinuclear platinum (II) complex,[Pt2 (μ-L) 3 (μ-HL)]· Cl· 3H2O· DMSO (1, HL= 4-Amino-5-
pyridin-4-yl-2, 4-dihydro-[1, 2, 4] triazole-3-thione, DMSO= dimethyl sulfoxide), has been …

Cancer cell death induced by ruthenium complexes

J Žakula, MD Nešić, M Matijević, M Stepić… - Biologia …, 2023 - ojs.pmf.uns.ac.rs
Cancer is a complex and often fatal disease characterized by uncontrolled cell division. The
most commonly used chemotherapeutics target rapidly dividing cancer cells but, at the same …

[PDF][PDF] ЦИТОТОКСИЧНОСТ ДИНУКЛЕАРНИХ КОМПЛЕКСА ПЛАТИНЕ (II) У ЕКСПЕРИМЕНТАЛНОМ МОДЕЛУ КАРЦИНОМА КОЛОНА МИША

ИР Васић - medf.kg.ac.rs
САЖЕТАК Увод: Синтетисано је девет динуклеарних комплекса платинe (II) опште
формуле {[Pt (L) Cl] 2 (μ-X)} 2+, где је L координовани амински/диамински лиганд, a X …