Production of shikimic acid
Shikimic acid is a key intermediate for the synthesis of the antiviral drug oseltamivir
(Tamiflu®). Shikimic acid can be produced via chemical synthesis, microbial fermentation …
(Tamiflu®). Shikimic acid can be produced via chemical synthesis, microbial fermentation …
Production and synthetic modifications of shikimic acid
NR Candeias, B Assoah, SP Simeonov - Chemical reviews, 2018 - ACS Publications
Shikimic acid is a natural product of industrial importance utilized as a precursor of the
antiviral Tamiflu. It is nowadays produced in multihundred ton amounts from the extraction of …
antiviral Tamiflu. It is nowadays produced in multihundred ton amounts from the extraction of …
A short overview on the medicinal chemistry of (—)-shikimic acid
A M. Estevez, R J. Estevez - Mini Reviews in Medicinal …, 2012 - benthamdirect.com
Shikimic acid, a natural compound is a key intermediate in the biosynthesis of amino acids.
Consequently, this derivative is widely present in many plants and has interesting biological …
Consequently, this derivative is widely present in many plants and has interesting biological …
Expanding horizons of shikimic acid: Recent progresses in production and its endless frontiers in application and market trends
G Rawat, P Tripathi, RK Saxena - Applied Microbiology and Biotechnology, 2013 - Springer
Shikimic acid is an industrially important chiral compound used as a key ingredient in
formulation of drug Oseltamivir phosphate (Tamiflu) for the treatment of swine/avian flu. The …
formulation of drug Oseltamivir phosphate (Tamiflu) for the treatment of swine/avian flu. The …
Current perspectives on applications of shikimic and aminoshikimic acids in pharmaceutical chemistry
DCD Quiroz, SB Carmona, F Bolívar… - Research and Reports …, 2014 - Taylor & Francis
Aromatic metabolism comprises the shikimic acid (SA) and the aminoshikimic acid (ASA)
pathways. The SA pathway is the common route for the biosynthesis of aromatic amino acids …
pathways. The SA pathway is the common route for the biosynthesis of aromatic amino acids …
Improvement of shikimic acid production in Escherichia coli with growth phase-dependent regulation in the biosynthetic pathway from glycerol
MY Lee, WP Hung, SH Tsai - World Journal of Microbiology and …, 2017 - Springer
Shikimic acid is an important metabolic intermediate with various applications. This paper
presents a novel control strategy for the construction of shikimic acid producing strains …
presents a novel control strategy for the construction of shikimic acid producing strains …
Total synthesis of (+)-pericosine B and (+)-pericosine C and their enantiomers by using the Baylis–Hillman reaction and ring-closing metathesis as key steps
YS Reddy, P Kadigachalam, RK Basak, APJ Pal… - Tetrahedron letters, 2012 - Elsevier
Total synthesis of (+)-pericosine B and (+)-pericosine C and their enantiomers by using the
Baylis–Hillman reaction and ring-closing metathesis as key steps - ScienceDirect Skip to main …
Baylis–Hillman reaction and ring-closing metathesis as key steps - ScienceDirect Skip to main …
Chemical constituents from the aerial parts of Euphorbia formosana Hayata and their chemotaxonomic significance
A phytochemical investigation of the aerial parts of Euphorbia formosana Hayata resulted in
the isolation of 33 compounds, including various derivatives of ellagic acid and gallic acid …
the isolation of 33 compounds, including various derivatives of ellagic acid and gallic acid …
A new efficient synthesis of oseltamivir phosphate (Tamiflu) from (−)-shikimic acid
HK Kim, KJJ Park - Tetrahedron Letters, 2012 - Elsevier
New synthesis of oseltamivir phosphate was accomplished in 9 steps with a 27% overall
yield from a readily available (−)-shikimic acid. Selective ring opening reaction of ketal and …
yield from a readily available (−)-shikimic acid. Selective ring opening reaction of ketal and …
Rational Discovery of (+) (S) Abscisic Acid as a Potential Antifungal Agent: a Repurposing Approach
MA Khedr, A Massarotti, ME Mohamed - Scientific Reports, 2018 - nature.com
Fungal infections are spreading widely worldwide, and the types of treatment are limited due
to the lack of diverse therapeutic agents and their associated side effects and toxicity. The …
to the lack of diverse therapeutic agents and their associated side effects and toxicity. The …