EditordAnaesthetists, general practitioners, surgeons, and dentists use local anaesthetics
(LA) in their daily practice. Insufficient analgesic effect may result from various causes …

Patients who are medically compromised may be at an increased risk of complications and
treatment errors following periodontal therapy. A review of the evidence on the topic is …

Background A recent case series suggested that surgery with wide-awake local anesthesia
is tolerated well by most foot and ankle patients. However, patients were assessed …

Objective: Lead toxicity is a common health problem worldwide. It is usually occupational but
sometime non-occupational toxicities are reported. Opium-related lead toxicity has been …

Lacerations are a common reason for patients to seek medical attention, and are often
acutely managed in the emergency department. Recent studies pertaining to closure …

Опиоидная анальгезия продолжает оставаться «золотым стандартом»
послеоперационного обезболивания в большинстве развитых стран. В то же время в …

Background Previous evidence suggests that opioid tolerant patients are less responsive to
local anesthetics (LAs) for postoperative pain management. Methods To determine whether …

В статье дано определение понятия послеоперационной боли, описаны особенности
болевого синдрома после кардиохирургических вмешательств. Основное внимание …

Background Peripheral nerve blocks effectively alleviate postoperative pain. Animal studies
and human research suggest that opioid tolerance may reduce the effectiveness of local …

Pain is the psychophysiological reaction of an entire organism to a damaging factor.
According to the literature, 30.0–75.0% of patients suffer from severe pain in the …