A major shift is happening within neurophysiology: a population doctrine is drawing level
with the single-neuron doctrine that has long dominated the field. Population-level ideas …

While memories are often thought of as flashbacks to a previous experience, they do not
simply conserve veridical representations of the past but must continually integrate new …

The medial prefrontal cortex (mPFC) has been proposed to link sensory inputs and
behavioral outputs to mediate the execution of learned behaviors. However, how such a link …

Cognitive flexibility, the ability to alter strategy according to changing stimulus-response-
reward relationships, is critical for updating learned behavior. Attentional set-shifting, a test …

Highly synchronous neuronal assembly activity is deemed essential for cognitive brain
function. In theory, such synchrony could coordinate multiple brain areas performing …

Frontal cortex is thought to underlie many advanced cognitive capacities, from self-control to
long term planning. Reflecting these diverse demands, frontal neural activity is notoriously …

Sensory processing is influenced by cognitive and behavioral states, but how these states
interact to modulate responses of individual neurons is unknown. We trained mice in a …

The execution of cognitive functions requires coordinated circuit activity across different
brain areas that involves the associated firing of neuronal assemblies. Here, we tested the …

The ability to associate reward-predicting stimuli with adaptive behavior is frequently
attributed to the prefrontal cortex, but the stimulus-specificity, spatial distribution, and stability …

Biological neural networks adapt and learn in diverse behavioral contexts. Artificial neural
networks (ANNs) have exploited biological properties to solve complex problems. However …