The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted, focusing on 2006 through October 2012 and …

Background Atrial fibrillation (AF) represents an increasing public health challenge with
profound social and economic implications. Methods A comprehensive synthesis and review …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted, focusing on 2006 through October 2012 and …

Adherence to therapies is a primary determinant of treatment success. Failure to adherence
is a serious problem which not only affects the patient but also the health care system …

Background: Patients with chronic obstructive pulmonary disease (COPD) often present with
severe acute exacerbations requiring hospital treatment. However, little is known about the …

1.1. Organization of Committee and Evidence Review (UPDATED) For new or updated text,
view the 2011 Focused Update and the 2011 Update on Dabigatran. Text supporting …

Chronic obstructive pulmonary disease (COPD) represents an increasing burden throughout
the world. COPD-related mortality is probably underestimated because of the difficulties …

Atrial fibrillation (AF) is the most common sustained cardiac rhythm disturbance, increasing
in prevalence with age. AF is often associated with structural heart disease, although a …

Background Acute exacerbations form a major component of the socioeconomic burden of
COPD. As yet, little information is available about the long-term outcome of patients who …

Rationale: There is a need to identify clinically meaningful predictors of mortality following
hospitalized COPD exacerbation. Objectives: The aim of this study was to systematically …