The circadian clock of Neurospora crassa
Circadian clocks organize our inner physiology with respect to the external world, providing
life with the ability to anticipate and thereby better prepare for major fluctuations in its …
life with the ability to anticipate and thereby better prepare for major fluctuations in its …
Post-translational modifications in circadian rhythms
The pace has quickened in circadian biology research. In particular, an abundance of
results focused on post-translational modifications (PTMs) is sharpening our view of …
results focused on post-translational modifications (PTMs) is sharpening our view of …
Quantitative proteomics reveals a dynamic interactome and phase-specific phosphorylation in the Neurospora circadian clock
Circadian systems are comprised of multiple proteins functioning together to produce
feedback loops driving robust, approximately 24 hr rhythms. In all circadian systems …
feedback loops driving robust, approximately 24 hr rhythms. In all circadian systems …
Physical interaction between VIVID and white collar complex regulates photoadaptation in Neurospora
CH Chen, BS DeMay, AS Gladfelter… - Proceedings of the …, 2010 - National Acad Sciences
Photoadaptation, the ability to attenuate a light response on prolonged light exposure while
remaining sensitive to escalating changes in light intensity, is essential for organisms to …
remaining sensitive to escalating changes in light intensity, is essential for organisms to …
Dynamic PER repression mechanisms in the Drosophila circadian clock: from on-DNA to off-DNA
JS Menet, KC Abruzzi, J Desrochers… - Genes & …, 2010 - genesdev.cshlp.org
Transcriptional feedback loops are central to the generation and maintenance of circadian
rhythms. In animal systems as well as Neurospora, transcriptional repression is believed to …
rhythms. In animal systems as well as Neurospora, transcriptional repression is believed to …
The phospho-code determining circadian feedback loop closure and output in Neurospora
In the negative feedback loop driving fungal and animal circadian oscillators, negative
elements (FREQUENCY [FRQ], PERIODS [PERs], and CRYPTOCHROMES [CRYs]) are …
elements (FREQUENCY [FRQ], PERIODS [PERs], and CRYPTOCHROMES [CRYs]) are …
Neurospora illuminates fungal photoreception
Light not only is indispensable as an energy source for life on earth but also serves as an
essential environmental cue conveying the information of daily and seasonal time to …
essential environmental cue conveying the information of daily and seasonal time to …
Protein sequestration versus Hill‐type repression in circadian clock models
JK Kim - IET systems biology, 2016 - Wiley Online Library
Circadian (∼ 24 h) clocks are self‐sustained endogenous oscillators with which organisms
keep track of daily and seasonal time. Circadian clocks frequently rely on interlocked …
keep track of daily and seasonal time. Circadian clocks frequently rely on interlocked …
Conserved RNA helicase FRH acts nonenzymatically to support the intrinsically disordered Neurospora clock protein FRQ
Protein conformation dictates a great deal of protein function. A class of naturally
unstructured proteins, termed intrinsically disordered proteins (IDPs), demonstrates that …
unstructured proteins, termed intrinsically disordered proteins (IDPs), demonstrates that …
FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora
Circadian clock mechanisms have been extensively investigated but the main rate-limiting
step that determines circadian period remains unclear. Formation of a stable complex …
step that determines circadian period remains unclear. Formation of a stable complex …