Neural circuit function can be drastically affected by variations in the number of cells that are
produced during development or by a reduction in adult cell number owing to disease. For …

Drosophila neuroblasts, the stem cells of the developing fly brain, have emerged as a key
model system for neural stem cell biology and have provided key insights into the …

Metabolic reprogramming is a key feature of many cancers, but how and when it contributes
to tumorigenesis remains unclear. Here we demonstrate that metabolic reprogramming …

The ability of cells to divide asymmetrically is essential for generating diverse cell types
during development. The past 10 years have seen tremendous progress in our …

The vast diversity of neurons and glia of the CNS is generated from a small, heterogeneous
population of progenitors that undergo transcriptional changes during development to …

The road to carbon nanotube transistors | Nature Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

A small pool of neural progenitors generates the vast diversity of cell types in the CNS.
Spatial patterning specifies progenitor identity, followed by temporal patterning within …

Cell division is commonly thought to involve the equal distribution of cellular components
into the two daughter cells. During many cell divisions, however, proteins, membrane …

In the mouse neocortex, neural progenitor cells generate both differentiating neurons and
daughter cells that maintain progenitor fate. Here, we show that the TRIM-NHL protein …

Stem cells are highly abundant during early development but become a rare population in
most adult organs. The molecular mechanisms causing stem cells to exit proliferation at a …