NF-κB pathway consists of canonical and non-canonical pathways. The canonical NF-κB is
activated by various stimuli, transducing a quick but transient transcriptional activity, to …

Tumor necrosis factor receptor (TNFR)-associated factors (TRAFs) are a family of structurally
related proteins that transduces signals from members of TNFR superfamily and various …

The NF-κB family of inducible transcription factors is activated in response to a variety of
stimuli. Amongst the best-characterized inducers of NF-κB are members of the TNF family of …

The mammalian stress-activated families of mitogen-activated protein kinases (MAPKs)
were first elucidated in 1994, and by 2001, substantial progress had been made in …

The non-canonical NF-κB pathway is an important arm of NF-κB signaling that
predominantly targets activation of the p52/RelB NF-κB complex. This pathway depends on …

The noncanonical nuclear factor‐κB (NF‐κB) signaling pathway mediates activation of the
p52/RelB NF‐κB complex and, thereby, regulates specific immunological processes. This …

The NF-κB family of transcription factors has an essential role in inflammation and innate
immunity. Furthermore, NF-κB is increasingly recognized as a crucial player in many steps of …

The intestinal epithelium constitutes an indispensable single-layered barrier to protect the
body from invading pathogens, antigens or toxins. At the same time, beneficial nutrients and …

Inflammation clearly occurs in pathologically vulnerable regions of the Alzheimer's disease
(AD) brain, and it does so with the full complexity of local peripheral inflammatory responses …

REVIEW Apoptosis is a cell suicide mechanism that enables metazoans to control cell
number in tissues and to eliminate individual cells that threaten the animal's survival. Certain …