[HTML][HTML] Immunological considerations for COVID-19 vaccine strategies

M Jeyanathan, S Afkhami, F Smaill, MS Miller… - Nature Reviews …, 2020 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is the most formidable challenge to …

[HTML][HTML] Adenovirus vectors: excellent tools for vaccine development

J Chang - Immune network, 2021 - ncbi.nlm.nih.gov
Adenovirus was originally used as a vector for gene therapy. In recent years, with the
development of the next-generation vectors with increased safety and high immunogenicity …

[HTML][HTML] Coronavirus infections: Epidemiological, clinical and immunological features and hypotheses

D Raoult, A Zumla, F Locatelli, G Ippolito, G Kroemer - Cell stress, 2020 - ncbi.nlm.nih.gov
Coronaviruses (CoVs) are a large family of enveloped, positive-strand RNA viruses. Four
human CoVs (HCoVs), the non-severe acute respiratory syndrome (SARS)-like HCoVs …

[HTML][HTML] Upper respiratory tract mucosal immunity for SARS-CoV-2 vaccines

R Fraser, A Orta-Resendiz, A Mazein… - Trends in molecular …, 2023 - cell.com
SARS-CoV-2 vaccination significantly reduces morbidity and mortality, but has less impact
on viral transmission rates, thus aiding viral evolution, and the longevity of vaccine-induced …

Tissue-specific differentiation of CD8+ resident memory T cells

K Yang, A Kallies - Trends in Immunology, 2021 - cell.com
CD8+ tissue-resident memory T (T RM) cells play crucial roles in defense against infections
and cancer and have been implicated in autoimmune diseases such as psoriasis. In mice …

[HTML][HTML] The roles of tissue-resident memory T cells in lung diseases

R Yuan, J Yu, Z Jiao, J Li, F Wu, R Yan… - Frontiers in …, 2021 - frontiersin.org
The unique environment of the lungs is protected by complex immune interactions. Human
lung tissue-resident memory T cells (TRM) have been shown to position at the pathogen …

Airway macrophages mediate mucosal vaccine–induced trained innate immunity against Mycobacterium tuberculosis in early stages of infection

MR D'Agostino, R Lai, S Afkhami, A Khera… - The Journal of …, 2020 - journals.aai.org
Mycobacterium tuberculosis, the causative agent of pulmonary tuberculosis (TB), is
responsible for millions of infections and deaths annually. Decades of TB vaccine …

[HTML][HTML] Bridging the gaps to overcome major hurdles in the development of next-generation tuberculosis vaccines

H Kim, HG Choi, SJ Shin - Frontiers in Immunology, 2023 - frontiersin.org
Although tuberculosis (TB) remains one of the leading causes of death from an infectious
disease worldwide, the development of vaccines more effective than bacille Calmette …

[HTML][HTML] Advancing Adjuvants for Mycobacterium tuberculosis Therapeutics

AB Enriquez, A Izzo, SM Miller, EL Stewart… - Frontiers in …, 2021 - frontiersin.org
Tuberculosis (TB) remains one of the leading causes of death worldwide due to a single
infectious disease agent. BCG, the only licensed vaccine against TB, offers limited protection …

Advancements in the characterization of tissue resident memory T cells in skin disease

L Li, PP Liu, C Chen, B Yan, X Chen, J Li, C Peng - Clinical Immunology, 2022 - Elsevier
The newly discovered subset of memory T cells, tissue resident memory T (TRM) cells,
reside in peripheral tissues for a long time, contributing to a rapid immune response and …