Novel prognostic clinical factors and biomarkers for outcome prediction in head and neck cancer: a systematic review

V Budach, I Tinhofer - The Lancet Oncology, 2019 - thelancet.com
Current algorithms for the clinical management of patients with squamous cell carcinoma of
the head and neck (HNSCC) are based on a stage-dependent strategy where all patients at …

[HTML][HTML] Prognostic and predictive value of EGFR in head and neck squamous cell carcinoma

P Bossi, C Resteghini, N Paielli, L Licitra, S Pilotti… - Oncotarget, 2016 - ncbi.nlm.nih.gov
EGFR is an extensively studied biomarker in head and neck squamous cell carcinoma
(HNSCC). In this review, we discuss the prognostic and predictive role of EGFR in HNSCC …

Novel genetic alterations and their impact on target therapy response in head and neck squamous cell carcinoma

X Jiang, J Ye, Z Dong, S Hu, M Xiao - Cancer Management and …, 2019 - Taylor & Francis
Head and neck squamous cell carcinoma (HNSCC) is highly variable by tumor site,
histologic type, molecular characteristics, and clinical outcome. During recent years …

Glycoprotein NMB promotes tumor formation and malignant progression of laryngeal squamous cell carcinoma

L Manevich, Y Okita, Y Okano, T Sugasawa… - Cancer …, 2022 - Wiley Online Library
Laryngeal squamous cell carcinoma (LSCC), although one of the most common head and
neck cancers, has a static or slightly decreased survival rate because of difficulties in early …

High expression of c‑Met and EGFR is associated with poor survival of patients with glottic laryngeal squamous cell carcinoma

M Jiang, H Zhang, H Xiao, Z Zhang… - Oncology …, 2018 - spandidos-publications.com
The present study was undertaken to explore the association between the expression of
hepatocyte growth factor receptor (c‑Met) and epidermal growth factor receptor (EGFR) with …

Nuclear EGFR expression is associated with poor survival in laryngeal carcinoma

B Marijić, T Braut, E Babarović, M Krstulja… - Applied …, 2021 - journals.lww.com
The membrane EGFR (mEGFR) protein overexpression in the head and neck squamous cell
carcinoma (SCC) is considered to cause increased EGFR activity which adds to …

Association between EGFR expression and clinical outcome of laryngeal HPV squamous cell carcinoma

M Kontić, Z Čolović, I Paladin, M Gabelica… - Acta oto …, 2019 - Taylor & Francis
Background: Expression of the epidermal growth factor receptor (EGFR) and human
papillomavirus (HPV) DNA can serve as independent prognostic factors in squamous cell …

VEGFR2 expression in head and neck squamous cell carcinoma cancer cells mediates proliferation and invasion

HM Xu, JG Zhu, L Gu, SQ Hu, H Wu - Asian Pacific Journal of …, 2016 - journal.waocp.org
Vascular endothelial growth factor 2 (VEGFR2) was initially identified as a receptor of VEGF
on endothelial cells with a role in regulating angiogenesis during organism development …

Combined EGFR/ALK expression analysis in laryngeal squamous cell carcinoma

A Politi, E Tsiambas, NS Mastronikolis, D Peschos… - in vivo, 2019 - iv.iiarjournals.org
Background/Aim: Epidermal growth factor receptor (EGFR) acts as an oncogene in
malignancies. Our aim was to examine the role of combined EGFR/anaplastic lymphoma …

EGFR cut-off point for prognostic impact in laryngeal squamous cell carcinoma

T Leesutipornchai, T Ratchataswan… - Acta Oto …, 2020 - Taylor & Francis
Background: Various molecular biomarkers, including epidermal growth factor receptor
(EGFR), have gained importance as predictors of head and neck cancer disease …