Background Afterload from moderate aortic stenosis (AS) may contribute to adverse
outcomes in patients with heart failure with reduced ejection fraction (HFrEF). Objectives The …

Aim Cardiac remodelling plays a major role in the prognosis of patients with aortic stenosis
(AS) and could impact the benefits of aortic valve replacement. Our study aimed to evaluate …

Aortic stenosis (AS) is associated with the development of replacement myocardial
fibrosis/scar. Given the dose-dependent relationship between scar and clinical outcomes …

Aortic stenosis (AS) is the commonest valve lesion requiring surgery in the Western world.
The presence of myocardial fibrosis is associated with mortality even after valve …

Purpose To investigate whether functional assessment of aberrant flow patterns by viscous
energy loss (E′ L) using four-dimensional (4D) flow MRI could determine aortic stenosis …

Introduction Guidelines recommend aortic valve replacement in patients with severe aortic
stenosis who present with symptoms or left ventricular ejection fraction< 50%, both …

Aortic stenosis (AS) causes chronic pressure overload in the left ventricle (LV) that ultimately
results in myocardial fibrosis. This fibrosis is associated with advanced symptoms, LV …