A new broad range plasmid for DNA delivery in eukaryotic cells using lactic acid bacteria: in vitro and in vivo assays

P Mancha-Agresti, MM Drumond… - … Therapy Methods & …, 2017 - cell.com
Lactococcus lactis is well documented as a promising candidate for development of novel
oral live vaccines. It has been broadly engineered for heterologous expression, as well as …

Precision Genome Engineering in Streptococcus suis Based on a Broad-Host-Range Vector and CRISPR-Cas9 Technology

A Gussak, ML Ferrando, M Schrama… - ACS synthetic …, 2023 - ACS Publications
Streptococcussuis is an important zoonotic pathogen that causes severe invasive disease in
pigs and humans. Current methods for genome engineering of S. suis rely on the insertion of …

Plasmid Replicons for the Production of Pharmaceutical-Grade pDNA, Proteins and Antigens by Lactococcus lactis Cell Factories

SOD Duarte, GA Monteiro - International Journal of Molecular Sciences, 2021 - mdpi.com
The Lactococcus lactis bacterium found in different natural environments is traditionally
associated with the fermented food industry. But recently, its applications have been …

Transformation of, and Heterologous Protein Expression in, Lactobacillus agilis and Lactobacillus vaginalis Isolates from the Chicken Gastrointestinal Tract

DP Stephenson, RJ Moore… - Applied and environmental …, 2011 - Am Soc Microbiol
Lactobacilli are naturally found in the gastrointestinal tract of chickens, and there is interest
in utilizing autochthonous strains for the delivery of therapeutic proteins. Previously we …

Loss of rpoE Encoding the δ-Factor of RNA Polymerase Impacts Pathophysiology of the Streptococcus pyogenes M1T1 Strain 5448

JS Rom, Y Le Breton, E Islam, AT Belew, NM El-Sayed… - Microorganisms, 2022 - mdpi.com
Streptococcus pyogenes, also known as the Group A Streptococcus (GAS), is a Gram-
positive bacterial pathogen of major clinical significance. Despite remaining relatively …

[图书][B] Characterization of the TRXSR two-component signal transduction system of Streptococcus pyogenes and its role in virulence regulation

KM Gold - 2011 - search.proquest.com
The Gram-positive group A streptococcus (GAS) is a strict human pathogen, which causes a
wide variety of infections, ranging in severity from minor to life threatening. In order to cause …

การ ศึกษา การ คง อยู่ ของ พ ลา ส มิด pHentAI ใน Bacillus subtilis

อร อนงค์ สม ทรัพย์… - ASEAN Journal of …, 2012 - ph02.tci-thaijo.org
Abstract โคลน ยีน แบค เท อริ โอ ซิ น entAI จาก Enterococcus faecium N15 เข้า สู่ Escherichia
coli DH5α และ Bacillus subtilis ISW1214 ด้วย พ ลา ส มิด พาหะ pHY300PLK ให้ ชื่อว่า pHentAI …