Local intravitreal or intra-arterial chemotherapy has improved therapeutic success for the
pediatric cancer retinoblastoma (RB), but toxicity remains a major caveat. RB initiates …

Retinoblastoma (RB) is a highly aggressive ocular tumor, and due to socioeconomic and
medical constraints, many children receive treatment only in the metaphase and advanced …

Purpose To evaluate the efficacy and toxicity of intravitreal carboplatin plus melphalan for
the treatment of vitreous seeds in eyes with retinoblastoma (RB). Methods This retrospective …

Purpose To determine the safety and toxicity profile of intravitreal carboplatin as salvage
treatment for retinoblastoma with vitreous disease. Design Single-institution, interventional …

To evaluate the ocular safety of intravitreal carboplatin and digoxin injections as a new
intravitreal chemotherapy option for retinoblastoma tumor vitreous seeds. Eighteen rabbits …

This August issue of I Clinical and Experimental Ophthalmology i includes two studies of
surgical outcomes for quite different paediatric eye diseases. Our paediatric ophthalmology …