An update on the mechanisms related to cell death and toxicity of doxorubicin and the protective role of nutrients
Doxorubicin (DOX), is a very effective chemotherapeutic agent against cancer whose clinical
use is limited by toxicity. Different strategies have been proposed to attenuate toxicity …
use is limited by toxicity. Different strategies have been proposed to attenuate toxicity …
The beneficial role of exercise in mitigating doxorubicin-induced Mitochondrionopathy
I Marques-Aleixo, E Santos-Alves, PJ Oliveira… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Doxorubicin (DOX) is a widely used antineoplastic agent for a wide range of cancers,
including hematological malignancies, soft tissue sarcomas and solid tumors. However …
including hematological malignancies, soft tissue sarcomas and solid tumors. However …
Resolvin E1 protects against doxorubicin-induced cardiotoxicity by inhibiting oxidative stress, autophagy and apoptosis by targeting AKT/mTOR signaling
J Zhang, M Wang, W Ding, M Zhao, J Ye, Y Xu… - Biochemical …, 2020 - Elsevier
Doxorubicin (DOX)-induced cardiotoxicity impairs the quality of life of cancer patients during
or after DOX treatment, and it is imperative to explore a novel strategy to address this …
or after DOX treatment, and it is imperative to explore a novel strategy to address this …
Long chain omega-3 polyunsaturated fatty acid supplementation alleviates doxorubicin-induced depressive-like behaviors and neurotoxicity in rats: involvement of …
YQ Wu, RL Dang, MM Tang, HL Cai, HD Li, DH Liao… - Nutrients, 2016 - mdpi.com
Doxorubicin (DOX) is a chemotherapeutic agent widely used in human malignancies. Its
long-term use can cause neurobiological side-effects associated with depression. Omega-3 …
long-term use can cause neurobiological side-effects associated with depression. Omega-3 …
[HTML][HTML] Zinc/alogliptin combination attenuates testicular toxicity induced by doxorubicin in rats: Role of oxidative stress, apoptosis and TGF-β1/NF-κB signaling
AM Kabel - Biomedicine & Pharmacotherapy, 2018 - Elsevier
The aim of this study was to assess the effect of alogliptin and/or zinc on doxorubicin (DOX)-
induced testicular toxicity in rats. Sixty male Wistar rats were divided into 6 equal groups …
induced testicular toxicity in rats. Sixty male Wistar rats were divided into 6 equal groups …
Exposure to oxyfluorfen-induced hematobiochemical alterations, oxidative stress, genotoxicity, and disruption of sex hormones in male African catfish and the potential …
AT Mansour, RM Amen, HH Mahboub… - … and Physiology Part C …, 2023 - Elsevier
The present study evaluated the effect of chronic exposure to oxyfluorfen (OXY) on different
physiological responses of male African catfish, Clarias gariepinus, and the ameliorative …
physiological responses of male African catfish, Clarias gariepinus, and the ameliorative …
Fluvastatin attenuates doxorubicin-induced testicular toxicity in rats by reducing oxidative stress and regulating the blood–testis barrier via mTOR signaling pathway
Doxorubicin (DOX) is an anthracycline derivative antibiotic that still frequently used in the
treatment of solid tumors and hematological malignancies. The clinical use of DOX is largely …
treatment of solid tumors and hematological malignancies. The clinical use of DOX is largely …
4‐Nonylphenol induces disruption of spermatogenesis associated with oxidative stress‐related apoptosis by targeting p53‐Bcl‐2/Bax‐Fas/FasL signaling
P Duan, C Hu, HJ Butler, C Quan… - Environmental …, 2017 - Wiley Online Library
Nonylphenol (NP) is a ubiquitous environmental chemical with estrogenic activity. Our aim
was to test the hypothesis that pubertal exposure to NP leads to testicular dysfunction …
was to test the hypothesis that pubertal exposure to NP leads to testicular dysfunction …
Protective effect of Gallic acid on doxorubicin‐induced testicular and epididymal toxicity
MJ Olusoji, OM Oyeyemi, ER Asenuga… - Andrologia, 2017 - Wiley Online Library
The effect of Gallic acid (GA) on doxorubicin (DOX)‐induced testicular and epididymal
toxicity was investigated in experimental rat model. The rats were randomly divided into six …
toxicity was investigated in experimental rat model. The rats were randomly divided into six …
Omega-3 fatty acid is a potential preventive agent for recurrent colon cancer
A Vasudevan, Y Yu, S Banerjee, J Woods… - Cancer Prevention …, 2014 - AACR
Increasing evidence supports the contention that many malignancies, including sporadic
colorectal cancer, are driven by the self-renewing, chemotherapy-resistant cancer stem/stem …
colorectal cancer, are driven by the self-renewing, chemotherapy-resistant cancer stem/stem …