[HTML][HTML] Rotaviruses

U Desselberger - Virus research, 2014 - Elsevier
Recent advances of rotavirus (RV) basic and applied research are reviewed. They consist of
determination of the RV particle structure and functions of structural proteins, classification …

Viroplasms: assembly and functions of rotavirus replication factories

G Papa, A Borodavka, U Desselberger - Viruses, 2021 - mdpi.com
Viroplasms are cytoplasmic, membraneless structures assembled in rotavirus (RV)-infected
cells, which are intricately involved in viral replication. Two virus-encoded, non-structural …

Histo-blood group antigens: a common niche for norovirus and rotavirus

M Tan, X Jiang - Expert reviews in molecular medicine, 2014 - cambridge.org
Noroviruses (NoVs) and rotaviruses (RVs), the two most important causes of viral acute
gastroenteritis, are found to recognise histo-blood group antigens (HBGAs) as receptors or …

Functional refolding of the penetration protein on a non-enveloped virus

T Herrmann, R Torres, EN Salgado, C Berciu… - Nature, 2021 - nature.com
A non-enveloped virus requires a membrane lesion to deliver its genome into a target cell.
For rotaviruses, membrane perforation is a principal function of the viral outer-layer protein …

Rotavirus NSP4 triggers secretion of proinflammatory cytokines from macrophages via toll-like receptor 2

Y Ge, A Mansell, JE Ussher, AES Brooks… - Journal of …, 2013 - Am Soc Microbiol
ABSTRACT Nonstructural protein 4 (NSP4), encoded by rotavirus, exhibits various
properties linked to viral pathogenesis, including enterotoxic activity. A recent study (OV …

[HTML][HTML] In situ structure of rotavirus VP1 RNA-dependent RNA polymerase

S Jenni, EN Salgado, T Herrmann, Z Li, T Grant… - Journal of molecular …, 2019 - Elsevier
Rotaviruses, like other non-enveloped, double-strand RNA viruses, package an RNA-
dependent RNA polymerase (RdRp) with each duplex of their segmented genomes …

VirusTAP: viral genome-targeted assembly pipeline

A Yamashita, T Sekizuka, M Kuroda - Frontiers in microbiology, 2016 - frontiersin.org
Although next-generation sequencing (NGS) technology provides a comprehensive means
with which to identify potential pathogens from clinical specimens, simple and user-friendly …

Rotavirus NSP1 protein inhibits interferon-mediated STAT1 activation

A Sen, L Rott, N Phan, G Mukherjee… - Journal of …, 2014 - Am Soc Microbiol
Rotavirus (RV) replicates efficiently in intestinal epithelial cells (IECs) in vivo despite the
activation of a local host interferon (IFN) response. Previously, we demonstrated that …

Rotavirus mRNAS are released by transcript-specific channels in the double-layered viral capsid

J Periz, C Celma, B Jing… - Proceedings of the …, 2013 - National Acad Sciences
Rotaviruses are the single most common cause of fatal and severe childhood diarrheal
illness worldwide (> 125 million cases annually). Rotavirus shares structural and functional …

Global infection rate of rotavirus C during 1980–2022 and analysis of critical factors in the host range restriction of virus VP4

S Zhao, X Jin, L Zang, Z Liu, X Wen, X Ran - Viruses, 2022 - mdpi.com
Information on rotavirus C (RVC) infection is lacking, partly because the prevalence of RVC
among humans and animals worldwide is undefined. Data on the characteristics of the P …