Bladder cancer is a complex disease with variable prognosis. Recent investigations into the
molecular landscape of bladder cancer have revealed frequent genetic alterations and …

Bladder cancer (BC) is a heterogeneous disease with highly variable clinical and
pathological features, and resulting in different outcomes. Such heterogeneity ensues from …

Simple Summary Our study aimed to apply a quantitative method based on mRNA counting
as nCounter (NanoString Technologies, Inc). This method can obtain precise and accurate …

Urothelial cancer (UC) care is moving toward precision oncology. For tumor biology–driven
treatment of metastatic UC (mUC), molecular subtypes play a crucial role. However, it is not …

Alternative therapeutic options targeting urologic malignancies, such as germ cell tumours,
as well as urothelial, renal and prostate carcinomas, are still urgently needed. The …

Aims Adjuvant chemotherapy after radical cystectomy can reduce the risk of recurrence and
death in advanced muscle-invasive urothelial bladder cancer (MIBC). Molecular subtypes …

Background We have previously identified an unsuspected role for GJB3 showing that the
deficiency of this connexin protein induces aneuploidy in human and murine cells and …

Introduction and Objective Identifying patients that benefit from cisplatin-based adjuvant
chemotherapy is a major issue in the management of muscle-invasive bladder cancer …

Objective The low detection rate of early-stage and small tumors remains a clinical
challenge. A solution to this unmet need is urgently warranted for the accurate diagnosis …

Simple Summary Our study used NanoString technology, a high-throughput platform
measuring gene expression at the mRNA level to identify a set of genes predictive of clinical …