The pentose phosphate pathway (PPP) is a fundamental component of cellular metabolism.
The PPP is important to maintain carbon homoeostasis, to provide precursors for nucleotide …

The trace element zinc is required for proper functioning of a large number of proteins,
including various enzymes. However, most zinc-containing proteins are transcription factors …

To understand regulatory systems, it would be useful to uniformly determine how different
components contribute to the expression of all other genes. We therefore monitored mRNA …

The sequence specificity of DNA-binding proteins is the primary mechanism by which the
cell recognizes genomic features. Here, we describe systematic determination of yeast …

Thiamin and thiamin pyrophosphate (TPP) are well known for their important roles in human
nutrition and enzyme catalysis. In this work, we present new evidence for an additional role …

Lignocellulose-based biorefineries have been gaining increasing attention to substitute
current petroleum-based refineries. Biomass processing requires a pretreatment step to …

Saccharomyces cerevisiae preferentially uses glucose as a carbon source, but following its
depletion, it can utilize a wide variety of other carbons including nonfermentable compounds …

The pentose phosphate pathway (PPP) is a route that can work in parallel to glycolysis in
glucose degradation in most living cells. It has a unidirectional oxidative part with glucose-6 …

Pretreatment of lignocellulose biomass for biofuel production generates inhibitory
compounds that interfere with microbial growth and subsequent fermentation. Remediation …

Lycopene is a red carotenoid pigment with strong antioxidant activity. Saccharomyces
cerevisiae is considered a promising host to produce lycopene, but lycopene toxicity is one …