Molecular characterization, expression and functional analysis of NOD1, NOD2 and NLRC3 in Nile tilapia (Oreochromis niloticus)

F Gao, J Pang, M Lu, H Zhu, X Ke, Z Liu, J Cao… - Fish & shellfish …, 2018 - Elsevier
The nucleotide-binding oligomerization domain proteins NOD1, NOD2 and NLRC3 are
cytoplasmic pattern recognition receptors (PRRs) of the Nod-like receptor (NLR) family. In …

Deciphering the ATP-binding mechanism (s) in NLRP-NACHT 3D models using structural bioinformatics approaches

J Maharana, D Panda, S De - PLoS One, 2018 - journals.plos.org
Nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs), the first line of
defense, are the cytosolic pattern recognition receptors (PRRs) that regulate the …

Bacterial peptidoglycan with amidated meso-diaminopimelic acid evades NOD1 recognition: an insight into NOD1 structure–recognition

S Vijayrajratnam, AC Pushkaran… - Biochemical …, 2016 - portlandpress.com
Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) is an intracellular
pattern recognition receptor that recognizes bacterial peptidoglycan (PG) containing meso …

Sodium valproate attenuates the iE-DAP induced inflammatory response by inhibiting the NOD1-NF-κB pathway and histone modifications in bovine mammary …

Q Gao, Y Wang, N Ma, H Dai, AC Roy, G Chang… - International …, 2020 - Elsevier
The anti-inflammatory effects of sodium valproate (VPA) in vivo and in vitro have been
demonstrated in recent studies. The aim of this study was to evaluate whether VPA can …

Discovery of 1, 4-Benzodiazepine-2, 5-dione (BZD) derivatives as dual nucleotide binding oligomerization domain containing 1/2 (NOD1/NOD2) antagonists …

S Wang, J Yang, X Li, Z Liu, Y Wu, G Si… - Journal of medicinal …, 2017 - ACS Publications
Nucleotide-binding oligomerization domain-like receptors (NLRs) are intracellular sensors
of pathogen-associated molecular patterns (PAMPs) and damage-associated molecular …

Molecular cloning, GTP recognition mechanism and tissue-specific expression profiling of myxovirus resistance (Mx) protein in Labeo rohita (Hamilton) after Poly I:C …

BK Das, P Roy, AK Rout, DR Sahoo, SP Panda… - Scientific reports, 2019 - nature.com
The myxovirus resistance (Mx) proteins belong to interferon-induced dynamin GTPase and
play pivotal role in the inhibition of replication of numerous viruses. These antiviral proteins …

Structural Models of Zebrafish (Danio rerio) NOD1 and NOD2 NACHT Domains Suggest Differential ATP Binding Orientations: Insights from Computational Modeling …

J Maharana, BR Sahoo, A Bej, I Jena, A Parida… - PLoS …, 2015 - journals.plos.org
Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) and NOD2 are
cytosolic pattern recognition receptors playing pivotal roles in innate immune signaling …

Structural elucidation of inter-CARD interfaces involved in NOD2 tandem CARD association and RIP2 recognition

J Maharana, D Maharana, A Bej… - The Journal of …, 2021 - ACS Publications
Nucleotide-binding and oligomerization domain-containing protein 2 (NOD2) recognizes the
muramyl dipeptide and activates the NF-κB signaling cascade following its interaction with …

Insights into structure and dynamics of extracellular domain of Toll-like receptor 5 in Cirrhinus mrigala (mrigala): A molecular dynamics simulation approach

AK Rout, V Acharya, D Maharana, B Dehury… - PloS one, 2021 - journals.plos.org
The toll-like receptor 5 (TLR5) is the most conserved important pattern recognition receptors
(PRRs) often stimulated by bacterial flagellins and plays a major role in the first-line defense …

Structural and functional insights into CARDs of zebrafish (Danio rerio) NOD1 and NOD2, and their interaction with adaptor protein RIP2

J Maharana, B Dehury, JR Sahoo, I Jena, A Bej… - Molecular …, 2015 - pubs.rsc.org
Nucleotide-binding and oligomerization domain-containing protein 1 (NOD1) and NOD2 are
cytosolic pattern-recognition receptors (PRRs) composed of an N-terminal caspase …