Effects of GH/IGF axis on bone and cartilage
Growth hormone (GH) and its mediator, the insulin-like growth factor-1 (IGF-1) regulate
somatic growth, metabolism and many aspects of aging. As such, actions of GH/IGF have …
somatic growth, metabolism and many aspects of aging. As such, actions of GH/IGF have …
Musculoskeletal effects of altered GH action
Growth hormone (GH) is a peptide hormone that can signal directly through its receptor or
indirectly through insulin-like growth factor 1 (IGF-1) stimulation. GH draws its name from its …
indirectly through insulin-like growth factor 1 (IGF-1) stimulation. GH draws its name from its …
Common and uncommon mouse models of growth hormone deficiency
Mouse models of growth hormone deficiency (GHD) have provided important tools for
uncovering the various actions of GH. Nearly 100 years of research using these mouse lines …
uncovering the various actions of GH. Nearly 100 years of research using these mouse lines …
A novel peptide antagonist of the human growth hormone receptor
Excess circulating human growth hormone (hGH) in vivo is linked to metabolic and growth
disorders such as cancer, diabetes, and acromegaly. Consequently, there is considerable …
disorders such as cancer, diabetes, and acromegaly. Consequently, there is considerable …
Disruption of growth hormone receptor in adipocytes improves insulin sensitivity and lifespan in mice
Growth hormone receptor knockout (GHRKO) mice have been used for 25 years to uncover
some of the many actions of growth hormone (GH). Since they are extremely long-lived with …
some of the many actions of growth hormone (GH). Since they are extremely long-lived with …
Transcriptome profiling of insulin sensitive tissues from GH deficient mice following GH treatment
Purpose Most studies that have examined the transcriptional response to GH have been
performed with a single tissue. Thus, the current study performed RNASeq across three …
performed with a single tissue. Thus, the current study performed RNASeq across three …
[HTML][HTML] Growth Hormone Gene Family and Its Evolution
In this review, we will analyze the family of growth hormone (GH) genes, the territories where
they are produced, the proteolytic generation of GH isoforms, both at the pituitary and tissue …
they are produced, the proteolytic generation of GH isoforms, both at the pituitary and tissue …
Early Investigations of 20-kDa Human Placental GH Show Promise
EO List, DE Berryman, BP List… - Endocrine, Metabolic & …, 2023 - ingentaconnect.com
Growth hormone (GH) is a 22-kDa polypeptide secreted from the anterior pituitary. While it is
well known for its role in controlling longitudinal bone growth, GH also acts on multiple …
well known for its role in controlling longitudinal bone growth, GH also acts on multiple …
Growth hormone
A Bartke, S Brannan - Anti-Aging Pharmacology, 2023 - Elsevier
Interest in growth hormone (GH; also known as somatotropin) as a potential anti-aging agent
stems primarily from the evidence that GH treatment in elderly individuals can reduce …
stems primarily from the evidence that GH treatment in elderly individuals can reduce …
Transcriptomic Analysis of a Variant of Growth Hormone with Therapeutic Potential
JA Bogart - 2023 - rave.ohiolink.edu
Growth hormone deficiency is a condition that results from insufficient production and
secretion of growth hormone (GH) from the pituitary gland. Since GH has numerous …
secretion of growth hormone (GH) from the pituitary gland. Since GH has numerous …