Protective role of kallistatin in vascular and organ injury

J Chao, G Bledsoe, L Chao - Hypertension, 2016 - Am Heart Assoc
534 Hypertension September 2016 vasodilation is unrelated to the tissue kallikrein–kinin
system. 18 In addition, kallistatin transgenic mice were found to have significantly lower …

MiR-21 in the cancers of the digestive system and its potential role as a diagnostic, predictive, and therapeutic biomarker

HT Nguyen, SEO Kacimi, TL Nguyen, KH Suman… - Biology, 2021 - mdpi.com
Simple Summary MicroRNAs are small, non-coding RNA molecules that can regulate the
expression of various cancer-related genes and thereby contribute to tumorigenesis and …

miR-21 induces endothelial progenitor cells proliferation and angiogenesis via targeting FASLG and is a potential prognostic marker in deep venous thrombosis

X Du, L Hong, L Sun, H Sang, A Qian, W Li… - Journal of translational …, 2019 - Springer
Background Deep venous thrombosis (DVT) of lower extremities is a common thrombotic
disease, occurring either in isolation or as a complication of other diseases or procedures …

Kallistatin protects against sepsis-related acute lung injury via inhibiting inflammation and apoptosis

WC Lin, CW Chen, YW Huang, L Chao, J Chao… - Scientific reports, 2015 - nature.com
Kallistatin, an endogenous plasma protein, exhibits pleiotropic properties in inhibiting
inflammation, oxidative stress and apoptosis, as evidenced in various animal models and …

MiR-21 up-regulation mediates glioblastoma cancer stem cells apoptosis and proliferation by targeting FASLG

C Shang, Y Guo, Y Hong, Y Liu, Y Xue - Molecular biology reports, 2015 - Springer
To investigate whether miR-21 can affect the apoptosis and proliferation of glioblastoma
cancer stem cells (GSCs) from down-regulating FASLG. The expression of miRNA-21 was …

Kallistatin induces breast cancer cell apoptosis and autophagy by modulating Wnt signaling and microRNA synthesis

P Li, Y Guo, G Bledsoe, Z Yang, L Chao… - Experimental cell research, 2016 - Elsevier
Kallistatin is an endogenous protein that regulates differential signaling pathways and
biological functions. Our previous studies showed that kallistatin gene therapy inhibited …

Multi-omics analysis of brain tissue metabolome and proteome reveals the protective effect of gross saponins of Tribulus terrestris L. fruit against ischemic stroke in rat

Y Wang, W Guo, S Xie, Y Liu, D Xu, G Chen… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Gross Saponins of Tribulus terrestris L. Fruit
(GSTTF) has been reported to have a protective effect against ischemic stroke, but the …

Iripin-3, a New Salivary Protein Isolated From Ixodes ricinus Ticks, Displays Immunomodulatory and Anti-Hemostatic Properties In Vitro

A Chlastáková, J Kotál, Z Beránková… - Frontiers in …, 2021 - frontiersin.org
Tick saliva is a rich source of pharmacologically and immunologically active molecules.
These salivary components are indispensable for successful blood feeding on vertebrate …

Activation of peroxisome proliferator-activated receptor gamma is crucial for antitumoral effects of 6-iodolactone

M Nava-Villalba, RE Nuñez-Anita, A Bontempo… - Molecular Cancer, 2015 - Springer
Background Molecular iodine (I 2) exhibits antiproliferative and apoptotic effects on in vivo
and in vitro cancer models. These effects are thought to be mediated by an iodinated …

Proteomic characterization of early lung response to breast cancer metastasis in mice

A Kurpińska, J Suraj, E Bonar, A Zakrzewska… - Experimental and …, 2019 - Elsevier
Introduction The tumor-promoting rearrangement of the lungs facilitates the process of
cancer cell survival in a foreign microenvironment and enables their protection against …