IPNA clinical practice recommendations for the diagnosis and management of children with steroid-sensitive nephrotic syndrome
Idiopathic nephrotic syndrome is the most frequent pediatric glomerular disease, affecting
from 1.15 to 16.9 per 100,000 children per year globally. It is characterized by massive …
from 1.15 to 16.9 per 100,000 children per year globally. It is characterized by massive …
Current understanding of the molecular mechanisms of circulating permeability factor in focal segmental glomerulosclerosis
The pathogenetic mechanisms underlying the onset and the post-transplant recurrence of
primary focal segmental glomerulosclerosis (FSGS) are complex and remain yet to be fully …
primary focal segmental glomerulosclerosis (FSGS) are complex and remain yet to be fully …
Expansion of Escherichia-Shigella in gut is associated with the onset and response to immunosuppressive therapy of IgA nephropathy
J Zhao, M Bai, X Ning, Y Qin, Y Wang… - Journal of the …, 2022 - journals.lww.com
Background Gut dysbiosis is postulated to participate in the pathogenesis of IgA
nephropathy (IgAN). However, the key bacterial taxa closely associated with IgAN onset and …
nephropathy (IgAN). However, the key bacterial taxa closely associated with IgAN onset and …
Membranous nephropathy: mechanistic insights and therapeutic perspectives
MR Hua, YL Zhao, JZ Yang, L Zou, YY Zhao… - International …, 2023 - Elsevier
Membranous nephropathy (MN) is one of the most common causes of non-diabetic
nephrotic syndrome in adults. About 80% of cases are renal limited (primary MN) and 20 …
nephrotic syndrome in adults. About 80% of cases are renal limited (primary MN) and 20 …
Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysis
Background In spite of its invasive nature and risks, kidney biopsy is currently required for
precise diagnosis of many chronic kidney diseases (CKDs). Here, we explored the …
precise diagnosis of many chronic kidney diseases (CKDs). Here, we explored the …
Use of eculizumab in crescentic IgA nephropathy: proof of principle and conundrum?
T Ring, BB Pedersen, G Salkus… - Clinical kidney …, 2015 - academic.oup.com
IgA nephropathy (IgAN) is characterized by a variable clinical course and multifaceted
pathophysiology. There is substantial evidence to suggest that complement activation plays …
pathophysiology. There is substantial evidence to suggest that complement activation plays …
Post-infectious glomerulonephritis
R Balasubramanian, SD Marks - Paediatrics and international child …, 2017 - Taylor & Francis
Post-infectious glomerulonephritis (PIGN) is one of the most common causes of acute
glomerulonephritis in children. Although post-streptococcal glomerulonephritis (PSGN) is …
glomerulonephritis in children. Although post-streptococcal glomerulonephritis (PSGN) is …
Developing treatments for chronic kidney disease in the 21st century
Chronic kidney disease (CKD) is a lethal and rapidly increasing burden on society. Despite
this, there are relatively few therapies in development for the treatment of CKD. Several …
this, there are relatively few therapies in development for the treatment of CKD. Several …
Circulating exosomal microRNAs as biomarkers of systemic lupus erythematosus
W Li, S Liu, Y Chen, R Weng, K Zhang, X He, C He - Clinics, 2020 - SciELO Brasil
OBJECTIVES: Many studies indicate that microRNAs (miRNAs) could be potential
biomarkers for various diseases. The purpose of this study was to investigate the clinical …
biomarkers for various diseases. The purpose of this study was to investigate the clinical …
Membranous nephropathy and anti‐podocytes antibodies: implications for the diagnostic workup and disease management
A Pozdzik, I Brochériou, C David… - BioMed research …, 2018 - Wiley Online Library
The discovery of circulating antibodies specific for native podocyte antigens has transformed
the diagnostic workup and greatly improved management of idiopathic membranous …
the diagnostic workup and greatly improved management of idiopathic membranous …