Opportunities and challenges for the use of common controls in sequencing studies
Genome-wide association studies using large-scale genome and exome sequencing data
have become increasingly valuable in identifying associations between genetic variants and …
have become increasingly valuable in identifying associations between genetic variants and …
Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cells
Exercise training is critical for the prevention and treatment of obesity, but its underlying
mechanisms remain incompletely understood given the challenge of profiling …
mechanisms remain incompletely understood given the challenge of profiling …
[HTML][HTML] Integrative machine learning approaches for predicting disease risk using multi-omics data from the UK Biobank
We train prediction and survival models using multi-omics data for disease risk identification
and stratification. Existing work on disease prediction focuses on risk analysis using …
and stratification. Existing work on disease prediction focuses on risk analysis using …
Single-cell dissection of obesity-exercise axis in adipose-muscle tissues
Regular physical exercise has long been recognized to reverse the effects of diet-induced
obesity, but the molecular mechanisms mediating these multi-tissue beneficial effects …
obesity, but the molecular mechanisms mediating these multi-tissue beneficial effects …
Association of ultra-rare genetic variants with epilepsy
MEK Musa - 2023 - tobias-lib.ub.uni-tuebingen.de
Epilepsy represents a wide spectrum of phenotypes with various etiologies and
comorbidities. Genetic predisposition to epilepsy is conferred by rare variants and common …
comorbidities. Genetic predisposition to epilepsy is conferred by rare variants and common …