[HTML][HTML] Mechanisms of long COVID and the path toward therapeutics

MJ Peluso, SG Deeks - Cell, 2024 - cell.com
Long COVID, a type of post-acute sequelae of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2)(PASC) defined by medically unexplained symptoms following …

Divergent adaptive immune responses define two types of long COVID

J Kervevan, I Staropoli, D Slama… - Frontiers in …, 2023 - frontiersin.org
Background The role of adaptive immune responses in long COVID remains poorly
understood, with contrasting hypotheses suggesting either an insufficient antiviral response …

Long COVID: Alice Evans, brucellosis, and reflections on infectious causes of chronic disease

TC Smith - Clinical Infectious Diseases, 2023 - academic.oup.com
Despite more than a century of research on the link between infection and chronic diseases,
we again find ourselves flummoxed by a new pathogen that causes long-term impairment …

[HTML][HTML] Long-term prognosis at 1.5 years after infection with wild-type strain of SARS-CoV-2 and Alpha, Delta, as well as Omicron variants

J Agergaard, JD Gunst, B Schiøttz-Christensen… - International Journal of …, 2023 - Elsevier
Objectives Knowledge is limited on how changing SARS-CoV-2 variants may translate into
different characteristics and affect the prognosis of patients with long COVID, especially …

Long-term Cardiovascular, Cerebrovascular, and Other Thrombotic Complications in COVID-19 Survivors: A Retrospective Cohort Study

JT Lim, W Liang En, AT Tay, D Pang… - Clinical Infectious …, 2024 - academic.oup.com
Background Growing evidence suggests that some coronavirus disease 2019 (COVID-19)
survivors experience a wide range of long-term postacute sequelae. We examined the …

Acute and long COVID-19 symptoms and associated factors in the omicron-dominant period: a nationwide survey via the online platform Wenjuanxing in China

Z Su, Y Li, Y Xie, Z Huang, A Cheng, X Zhou, J Li… - BMC Public Health, 2024 - Springer
Backgrounds To our knowledge, there is no available nationwide data on omicron symptom
patterns in China mainland. We aim to determine the acute and long COVID-19 symptoms in …

Long-term neuropsychiatric sequelae of Delta versus Omicron SARS-CoV-2 infection

LE Wee, JT Lim, AT Tay, D Pang, B Dickens… - Clinical Microbiology …, 2024 - Elsevier
Objectives Studies have reported increased rates of long-term neuropsychiatric sequelae
after SARS-CoV-2 infection using electronic health-record (EHR) data; however, the majority …

Clinical coding of long COVID in primary care 2020–2023 in a cohort of 19 million adults: an OpenSAFELY analysis

AD Henderson, BFC Butler-Cole, J Tazare… - …, 2024 - thelancet.com
Background Long COVID is the patient-coined term for the persistent symptoms of COVID-
19 illness for weeks, months or years following the acute infection. There is a large burden of …

Distinct temporal trajectories and risk factors for Post-acute sequelae of SARS-CoV-2 infection

C Chen, S Parthasarathy, JM Leung, MJ Wu… - Frontiers in …, 2023 - frontiersin.org
Background The understanding of Post-acute sequelae of SARS-CoV-2 infection (PASC)
can be improved by longitudinal assessment of symptoms encompassing the acute illness …

Impact of COVID-19 infection on health-related quality of life, work productivity and activity impairment by symptom-based long COVID status and age in the US

M Di Fusco, JC Cappelleri, L Anatale-Tardiff, H Coetzer… - Healthcare, 2023 - mdpi.com
COVID-19 infection adversely impacts patients' wellbeing and daily lives. This survey-based
study examined differences in patient-reported COVID-19 symptoms, Health-Related Quality …