Macrophage migration inhibitory factor (MIF) is a cytokine expressed in various cell types,
including hematopoietic, epithelial, endothelial, mesenchymal and neuronal cells. Altered …

The role of macrophage migration inhibitory factor (MIF) in autoimmunity is underscored by
data showing that common functional polymorphisms in MIF are associated with disease …

The macrophage migration inhibitory factor (MIF) receptor (CD74) was cloned recently, but
the signaling mechanism is not evident. We hypothesized that signaling requires an …

Abstract The phosphoinositide-3-kinase (PI3K)/Akt signaling pathway plays an important
role in cell survival and the development of cancer. Macrophage migration inhibitory factor …

Rheumatoid arthritis is a multisystemic auto-inflammatory disease affecting up to 1% of the
population and leading to the destruction of the joints. Evidence exists for the involvement of …

The cytokine macrophage migration inhibitory factor (MIF) occupies a unique position in
physiology by its ability to directly regulate the immunosuppressive actions of …

Cell migration is essential for many biological processes in animals and is a complex highly
co‐ordinated process that involves cell polarization, actin‐driven protrusion and formation …

Chemokines orchestrate leukocyte recruitment in atherosclerosis and their blockade is a
promising anti-atherosclerotic strategy, but few chemokine-based approaches have …

Macrophage migration inhibitory factor (MIF) was originally identified for its ability to inhibit
the random migration of macrophages in vitro. MIF is now recognized as an important …

Macrophage migration inhibitory factor (MIF) has been defined as an important chemokine-
like function (CLF) chemokine with an essential role in monocyte recruitment and arrest …