When Szent-Györgyi called water the “matrix of life”, 1 he was echoing an old sentiment.
Paracelsus in the 16th century said that “water was the matrix of the world and of all its …

The advent of laser-based sources of ultrafast infrared pulses has extended the study of very
fast molecular dynamics to the observation of processes manifested through their effects on …

Hydrophobic hydration, the perturbation of the aqueous solvent near an apolar solute or
interface, is a fundamental ingredient in many chemical and biological processes. Both bulk …

Solvation free energy changes induced by protein folding and function are comparable to
the corresponding overall free energy changes. Yet the structure, dynamics, and energetics …

Quasielastic neutron scattering (QENS) experiments carried out using time-of-flight and
backscattering neutron spectrometers with widely different energy resolution and dynamic …

The heterogeneous nature of a protein surface plays an essential role in its biological
activity and molecular recognition, and this role is mediated at least partly through the …

We have performed two molecular-dynamics simulations to study the structural and
dynamical properties of water at the interface with phospholipid bilayers. In one of the …

We have studied the solvation of model peptides at low hydration levels by terahertz
absorption spectroscopy. We have recorded the concentration-dependent terahertz …

Water 2H and 17O spin relaxation is used to study water dynamics in the hydration layers of
two small peptides, two globular proteins and in living cells of two microorganisms. The …

Incoherent quasi-elastic neutron scattering (QENS) has been used to measure the dynamics
of water molecules in solutions of a model protein backbone, N-acetyl-glycine-methylamide …