Charge-reversal biodegradable MSNs for tumor synergetic chemo/photothermal and visualized therapy

Z Li, Y Yang, H Wei, X Shan, X Wang, M Ou… - Journal of Controlled …, 2021 - Elsevier
Given the difficulties of biodegradation of mesoporous silica nanoparticles (NPs),
enrichment and penetration of tumor sites, and real-time monitoring of the treatment process …

Poly (2‐oxazoline) s: a comprehensive overview of polymer structures and their physical properties—an update

S Jana, R Hoogenboom - Polymer International, 2022 - Wiley Online Library
Abstract Poly (2‐alkyl/aryl‐2‐oxazoline) s (PAOxs) have gained immense attraction in the
polymer research community because of their relative ease of microwave‐assisted …

Poly (2-oxazoline)-derived star-shaped polymers as potential materials for biomedical applications: A review

MN Leiske - European Polymer Journal, 2023 - Elsevier
Abstract Poly (2-oxazoline) s (POx) are a unique class of polymers with an enormous
potential for the preparation of functional materials. Their synthesis via the cationic ring …

The future of poly (2-oxazoline) s

R Hoogenboom - European Polymer Journal, 2022 - Elsevier
Abstract Poly (2-oxazoline) s have gained significant interest in the past decade, especially
driven by their high potential for biomedical applications, amongst others to substitute poly …

Tailored Monoacyl Poly (2-oxazoline)-and Poly (2-oxazine)-Lipids as PEG-Lipid Alternatives for Stabilization and Delivery of mRNA-Lipid Nanoparticles

X He, TJ Payne, A Takanashi, Y Fang… - …, 2024 - ACS Publications
The successful use of lipid nanoparticles (LNPs) for clinical development of the COVID-19
mRNA vaccines marked a breakthrough in mRNA-LNP therapeutics. As one of the vital …

Amidation of methyl ester-functionalised poly (2-oxazoline) s as a powerful tool to create dual pH-and temperature-responsive polymers as potential drug delivery …

MN Leiske, R Singha, S Jana, BG De Geest… - Polymer …, 2023 - pubs.rsc.org
In the past two decades, thermoresponsive polymers based on tertiary amine groups have
been studied extensively as a class of dual-responsive polymers. In particular, their …

Poly (2-oxazoline)–Ferrostatin-1 drug conjugates inhibit ferroptotic cell death

JP Morrow, ZAI Mazrad, AI Bush, K Kempe - Journal of Controlled Release, 2022 - Elsevier
Ferroptosis is a form of non-apoptotic iron induced cell death mechanism implicated in
neurodegeneration, yet can be ameliorated with potent radical scavengers such as …

[HTML][HTML] Impact of the polymer backbone chemistry on interactions of amino-acid-derived zwitterionic polymers with cells

MN Leiske, BG De Geest, R Hoogenboom - Bioactive Materials, 2023 - Elsevier
Zwitterionic polymers are known to interact with cells and have been shown to reveal cancer
cell specificity. In this work, the importance of the chemistry of the polymer backbone for the …

Comparison of the hydrophilicity of water-soluble poly (2-alkyl-2-oxazoline) s, poly (2-alkyl-2-oxazine) s and poly (2, 4-dialkyl-2-oxazoline) s

K Mint, JP Morrow, NM Warne, X He, D Pizzi… - Polymer …, 2024 - pubs.rsc.org
Poly (cyclic imino ether) s (PCIEs) including poly (2-alkyl-2-oxazoline) s (POx), poly (2-alkyl-
2-oxazine) s (POz) and poly (2, 4-dialkyl-2-oxazoline) s (PdOx) are a rapidly emerging …

Antifouling Properties of Poly (2‐Oxazoline) s and Poly (2‐Oxazine) s: Direct Comparison of Polymer‐Coated Surfaces with the Same Coating Parameters

J Svoboda, N Lusiani, R Sivkova… - Macromolecular …, 2023 - Wiley Online Library
This study presents a systematic comparison of the antifouling properties of water‐soluble
poly (2‐oxazoline)(PAOx) and poly (2‐oxazine)(PAOzi) brushes grafted to gold surfaces …