Protein analysis by shotgun/bottom-up proteomics

Y Zhang, BR Fonslow, B Shan, MC Baek… - Chemical …, 2013 - ACS Publications
According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …

Mass spectrometry: recent advances in direct open air surface sampling/ionization

ME Monge, GA Harris, P Dwivedi… - Chemical …, 2013 - ACS Publications
This review discusses advances in the field of ambient sampling/ionization mass
spectrometry (“ambient MS” for short) with a focus on mechanistic and instrumentation …

[HTML][HTML] Unraveling the mechanism of electrospray ionization

L Konermann, E Ahadi, AD Rodriguez, S Vahidi - 2013 - ACS Publications
Electrospray ionization (ESI) generates intact gas-phase ions from analytes in solution for
mass spectrometric investigations. ESI can proceed via different mechanisms. Low …

Ambient sampling/ionization mass spectrometry: applications and current trends

GA Harris, AS Galhena, FM Fernandez - Analytical chemistry, 2011 - ACS Publications
This biennial review discusses advances in the field of ambient sampling/ionization mass
spectrometry (“ambient MS” for short) in the period ranging from January 2009 to January …

Mechanisms of real-time, proximal sample processing during ambient ionization mass spectrometry

AR Venter, KA Douglass, JT Shelley… - Analytical …, 2014 - ACS Publications
In this review we highlight the general change in perception in the field of ambient mass
spectrometry that it is the immediacy of sample preparation that differentiates the ambient …

MALDI FTICR IMS of intact proteins: using mass accuracy to link protein images with proteomics data

JM Spraggins, DG Rizzo, JL Moore… - Journal of the …, 2015 - ACS Publications
MALDI imaging mass spectrometry is a highly sensitive and selective tool used to visualize
biomolecules in tissue. However, identification of detected proteins remains a difficult task …

Ambient ionization mass spectrometry: real-time, proximal sample processing and ionization

R Javanshad, AR Venter - Analytical Methods, 2017 - pubs.rsc.org
The definition of ambient ionization is updated from “no sample preparation” to sample
preparation proximal and in real time with the ionization and analysis step. We differentiate …

Recent methodological advances in MALDI mass spectrometry

K Dreisewerd - Analytical and bioanalytical chemistry, 2014 - Springer
Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is widely used
for characterization of large, thermally labile biomolecules. Advantages of this analytical …

Solvent assisted inlet ionization: an ultrasensitive new liquid introduction ionization method for mass spectrometry

VS Pagnotti, ND Chubatyi, CN McEwen - Analytical chemistry, 2011 - ACS Publications
A new inlet ionization method requiring no voltage or laser, and using water, methanol, or
water/organic solvent mixtures, is shown to produce mass spectra similar to those obtained …

A mechanism for ionization of nonvolatile compounds in mass spectrometry: considerations from MALDI and inlet ionization

S Trimpin, B Wang, ED Inutan, J Li… - Journal of The …, 2012 - ACS Publications
Mechanistic arguments relative to matrix-assisted laser desorption/ionization (MALDI) mass
spectrometry (MS) address observations that predominately singly charged ions are …