LncRNAs as potential diagnostic and prognostic biomarkers in gastric cancer: a novel approach to personalized medicine

S Fattahi, M Kosari‐Monfared… - Journal of cellular …, 2020 - Wiley Online Library
Gastric cancer is the third leading cause of cancer death with 5‐year survival rate of about
30–35%. Since early detection is associated with decreased mortality, identification of novel …

Long non-coding RNA signature in gastric cancer

S Ghafouri-Fard, M Taheri - Experimental and Molecular Pathology, 2020 - Elsevier
Gastric cancer as a common human malignancy has been associated with aberrant
expressions of several coding and non-coding genes. Long non-coding RNAs (lncRNAs) as …

HOTAIR long noncoding RNA promotes gastric cancer metastasis through suppression of poly r (C)-binding protein (PCBP) 1

ZZ Zhang, ZY Shen, YY Shen, EH Zhao, M Wang… - Molecular cancer …, 2015 - AACR
The objective of this study was to evaluate the role of HOTAIR long noncoding RNA in
gastric cancer metastasis. We analyzed HOTAIR expression levels by real-time reverse …

[HTML][HTML] Recent advances in the molecular diagnostics of gastric cancer

M Kanda, Y Kodera - World Journal of Gastroenterology: WJG, 2015 - ncbi.nlm.nih.gov
Gastric cancer (GC) is the third most common cause of cancer-related death in the world,
representing a major global health issue. Although the incidence of GC is declining, the …

[HTML][HTML] MiR-326 regulates cell proliferation and migration in lung cancer by targeting phox2a and is regulated by HOTAIR

R Wang, X Chen, T Xu, R Xia, L Han… - American journal of …, 2016 - ncbi.nlm.nih.gov
Recent findings indicate that microRNAs (miRNAs) play a crucial role in lung cancer
development, progression and regression. In our previous study, we identified miR-326 is …

HOTAIR induces the ubiquitination of Runx3 by interacting with Mex3b and enhances the invasion of gastric cancer cells

M Xue, L Chen, W Wang, T Su, L Shi, L Wang… - Gastric Cancer, 2018 - Springer
Abstract Background Long non-coding RNAs (LncRNAs) exert their functions mainly by
binding to their corresponding proteins. Runt-related transcription factor 3 (Runx3) is an …

The contrary functions of lnc RNA HOTAIR/miR‐17‐5p/PTEN axis and Shenqifuzheng injection on chemosensitivity of gastric cancer cells

J Jia, D Zhan, J Li, Z Li, H Li… - Journal of cellular and …, 2019 - Wiley Online Library
This study was implemented to figure out whether lnc RNA HOTAIR/miR‐17‐5p/PTEN axis
played a role that was opposite to Shenqifuzheng (SQFZ) injection in regulating the …

[HTML][HTML] Long noncoding RNAs in gastric cancer: from molecular dissection to clinical application

Y Gao, JW Wang, JY Ren, M Guo, CW Guo… - World journal of …, 2020 - ncbi.nlm.nih.gov
Long noncoding RNAs (lncRNAs) are important regulators of cell processes that are usually
dysregulated in gastric cancer (GC). Based on their high specificity and ease of detection in …

Plasma long non-coding RNA HOTAIR as a potential biomarker for gastric cancer

ET Elsayed, PE Salem, AM Darwish… - … journal of biological …, 2018 - journals.sagepub.com
Background: Long non-coding RNAs (lncRNAs) Hox transcript antisense intergenic RNA
(HOTAIR) has been suggested to be implicated in gastric cancer tumorigenesis and …

Long non-coding RNAs as the critical factors during tumor progressions among Iranian population: an overview

Z Rahmani, M Mojarrad, M Moghbeli - Cell & bioscience, 2020 - Springer
Background Cancer is associated with various genetic and environmental risk factors.
Beside the mutations or aberrant expression of protein-coding genes, the genetic …