The burden and etiology of diarrheal illness in developing countries

KL Kotloff - Pediatric Clinics, 2017 - pediatric.theclinics.com
Diarrheal disease is characterized by the onset of loose stools with or without vomiting,
which may be associated with systemic manifestations, such as fever and abdominal …

Effects of poverty on interacting biological systems underlying child development

SKG Jensen, AE Berens, CA Nelson - The Lancet Child & …, 2017 - thelancet.com
The developmental sequelae of childhood poverty are well documented. However, it is not
poverty per se, but a multitude of risk factors associated with poverty that have a deleterious …

Use of quantitative molecular diagnostic methods to investigate the effect of enteropathogen infections on linear growth in children in low-resource settings …

ET Rogawski, J Liu, JA Platts-Mills, F Kabir… - The Lancet Global …, 2018 - thelancet.com
Background Enteropathogen infections in early childhood not only cause diarrhoea but
contribute to poor growth. We used molecular diagnostics to assess whether particular …

[HTML][HTML] Use of antibiotics in children younger than two years in eight countries: a prospective cohort study

ET Rogawski, JA Platts-Mills, JC Seidman… - Bulletin of the World …, 2017 - ncbi.nlm.nih.gov
Objective To describe the frequency and factors associated with antibiotic use in early
childhood, and estimate the proportion of diarrhoea and respiratory illnesses episodes …

Gut microbiome alteration in MORDOR I: a community-randomized trial of mass azithromycin distribution

T Doan, A Hinterwirth, L Worden, AM Arzika, R Maliki… - Nature medicine, 2019 - nature.com
The MORDOR I trial, conducted in Niger, Malawi and Tanzania, demonstrated that mass
azithromycin distribution to preschool children reduced childhood mortality. However, the …

Controlled human infection models to accelerate vaccine development

RKM Choy, AL Bourgeois… - Clinical Microbiology …, 2022 - Am Soc Microbiol
The timelines for developing vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …

Campylobacter vaccination reduces diarrheal disease and infant growth stunting among rhesus macaques

SM Hendrickson, A Thomas, HP Raué… - Nature …, 2023 - nature.com
Campylobacter-associated enteric disease is estimated to be responsible for more than 160
million cases of gastroenteritis each year and is linked to growth stunting of infants living …

Global disease burden of pathogens in animal source foods, 2010

M Li, AH Havelaar, S Hoffmann, T Hald, MD Kirk… - PloS one, 2019 - journals.plos.org
Animal source foods (ASF) such as dairy, eggs, fish and meat are an important source of
high-quality nutrients. Lack of ASF in diets can result in developmental disorders including …

Relationship between growth and illness, enteropathogens and dietary intakes in the first 2 years of life: findings from the MAL-ED birth cohort study

Mal-Ed Network Investigators - BMJ global health, 2017 - gh.bmj.com
Background Dietary and illness factors affect risk of growth faltering; the role of
enteropathogens is less clear. As part of the Etiology, Risk Factors and Interactions of …

Current and Potential Treatments for Reducing Campylobacter Colonization in Animal Hosts and Disease in Humans

TJ Johnson, JM Shank, JG Johnson - Frontiers in microbiology, 2017 - frontiersin.org
Campylobacter jejuni is the leading cause of bacteria-derived gastroenteritis worldwide. In
the developed world, Campylobacter is usually acquired by consuming under-cooked …