Lyme disease in humans

JD Radolf, K Strle, JE Lemieux, F Strle - Current issues in molecular …, 2021 - mdpi.com
Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …

[HTML][HTML] Post-treatment Lyme disease as a model for persistent symptoms in Lyme disease

AW Rebman, JN Aucott - Frontiers in medicine, 2020 - frontiersin.org
It has long been observed in clinical practice that a subset of patients with Lyme disease
report a constellation of symptoms such as fatigue, cognitive difficulties, and musculoskeletal …

Development of an mRNA-lipid nanoparticle vaccine against Lyme disease

M Pine, G Arora, TM Hart, E Bettini, BT Gaudette… - Molecular Therapy, 2023 - cell.com
Lyme disease is the most common vector-borne infectious disease in the United States, in
part because a vaccine against it is not currently available for humans. We propose utilizing …

Citizen science informs human-tick exposure in the Northeastern United States

WT Porter, PJ Motyka, J Wachara, ZA Barrand… - International Journal of …, 2019 - Springer
Background Tick-borne disease is the result of spillover of pathogens into the human
population. Traditionally, literature has focused on characterization of tick-borne disease …

The evolving story of Borrelia burgdorferi sensu lato transmission in Europe

A Steinbrink, K Brugger, G Margos, P Kraiczy… - Parasitology …, 2022 - Springer
Beside mosquitoes, ticks are well-known vectors of different human pathogens. In the
Northern Hemisphere, Lyme borreliosis (Eurasia, LB) or Lyme disease (North America, LD) …

A glucose meter interface for point-of-care gene circuit-based diagnostics

E Amalfitano, M Karlikow, M Norouzi, K Jaenes… - Nature …, 2021 - nature.com
Recent advances in cell-free synthetic biology have given rise to gene circuit-based sensors
with the potential to provide decentralized and low-cost molecular diagnostics. However, it …

Ticks and tick-borne infections: complex ecology, agents, and host interactions

SK Wikel - Veterinary Sciences, 2018 - mdpi.com
Ticks transmit the most diverse array of infectious agents of any arthropod vector. Both ticks
and the microbes they transmit are recognized as significant threats to human and veterinary …

[HTML][HTML] Climate crises and developing vector-borne diseases: a narrative review

N Mojahed, MA Mohammadkhani… - Iranian journal of …, 2022 - ncbi.nlm.nih.gov
Background: Climate change based on temperature, humidity and wind can improve many
characteristics of the arthropod carrier life cycle, including survival, arthropod population …

Trained immunity: A “new” weapon in the fight against infectious diseases

A Dagenais, C Villalba-Guerrero, M Olivier - Frontiers in Immunology, 2023 - frontiersin.org
Innate immune cells can potentiate the response to reinfection through an innate form of
immunological memory known as trained immunity. The potential of this fast-acting …

The emergence and shift in seasonality of Lyme borreliosis in Northern Europe

A Goren, H Viljugrein, IM Rivrud… - … of the Royal …, 2023 - royalsocietypublishing.org
Climate change has had a major impact on seasonal weather patterns, resulting in marked
phenological changes in a wide range of taxa. However, empirical studies of how changes …