Molecularly targetable cell types in mouse visual cortex have distinguishable prediction error responses

SM O'Toole, HK Oyibo, GB Keller - Neuron, 2023 - cell.com
Predictive processing postulates the existence of prediction error neurons in cortex. Neurons
with both negative and positive prediction error response properties have been identified in …

Functional connectomics spanning multiple areas of mouse visual cortex

MICrONS Consortium, JA Bae, M Baptiste, CA Bishop… - BioRxiv, 2021 - biorxiv.org
To understand the brain we must relate neurons' functional responses to the circuit
architecture that shapes them. Here, we present a large functional connectomics dataset …

Neuronal parts list and wiring diagram for a visual system

A Matsliah, S Yu, K Kruk, D Bland, AT Burke, J Gager… - Nature, 2024 - nature.com
A catalogue of neuronal cell types has often been called a 'parts list'of the brain, and
regarded as a prerequisite for understanding brain function,. In the optic lobe of Drosophila …

[HTML][HTML] Cooperative thalamocortical circuit mechanism for sensory prediction errors

S Furutachi, AD Franklin, AM Aldea, TD Mrsic-Flogel… - Nature, 2024 - nature.com
The brain functions as a prediction machine, utilizing an internal model of the world to
anticipate sensations and the outcomes of our actions. Discrepancies between expected …

Synaptic architecture of leg and wing premotor control networks in Drosophila

E Lesser, AW Azevedo, JS Phelps, L Elabbady, A Cook… - Nature, 2024 - nature.com
Animal movement is controlled by motor neurons (MNs), which project out of the central
nervous system to activate muscles. MN activity is coordinated by complex premotor …

Transcriptomic cell-type specificity of local cortical circuits

M Patiño, MA Rossa, WN Lagos, NS Patne… - Neuron, 2024 - cell.com
Complex neocortical functions rely on networks of diverse excitatory and inhibitory neurons.
While local connectivity rules between major neuronal subclasses have been established …

[HTML][HTML] CAVE: Connectome annotation versioning engine

S Dorkenwald, CM Schneider-Mizell, D Brittain… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Abstract Advances in Electron Microscopy, image segmentation and computational
infrastructure have given rise to large-scale and richly annotated connectomic datasets …

Towards a foundation model of the mouse visual cortex

EY Wang, PG Fahey, K Ponder, Z Ding, A Chang… - bioRxiv, 2023 - biorxiv.org
Understanding the brain's perception algorithm is a highly intricate problem, as the inherent
complexity of sensory inputs and the brain's nonlinear processing make characterizing …

Functional connectomics reveals general wiring rule in mouse visual cortex

Z Ding, PG Fahey, S Papadopoulos, EY Wang… - …, 2024 - pmc.ncbi.nlm.nih.gov
Understanding the relationship between circuit connectivity and function is crucial for
uncovering how the brain implements computation. In the mouse primary visual cortex (V1) …

Combined topological and spatial constraints are required to capture the structure of neural connectomes

A Salova, IA Kovács - Network Neuroscience, 2024 - direct.mit.edu
Volumetric brain reconstructions provide an unprecedented opportunity to gain insights into
the complex connectivity patterns of neurons in an increasing number of organisms. Here …