What macromolecular crowding can do to a protein

IM Kuznetsova, KK Turoverov, VN Uversky - International journal of …, 2014 - mdpi.com
The intracellular environment represents an extremely crowded milieu, with a limited amount
of free water and an almost complete lack of unoccupied space. Obviously, slightly salted …

[HTML][HTML] Hybrid ceramic membranes for organic solvent nanofiltration: State-of-the-art and challenges

RB Merlet, MA Pizzoccaro-Zilamy, A Nijmeijer… - Journal of membrane …, 2020 - Elsevier
Uniquely suited to organic solvent nanofiltration (OSN) are hybrid, ceramic-based
membranes. The stability of these membranes in the harsh solvents and conditions of …

Vertically aligned and continuous nanoscale ceramic–polymer interfaces in composite solid polymer electrolytes for enhanced ionic conductivity

X Zhang, J Xie, F Shi, D Lin, Y Liu, W Liu, A Pei… - Nano …, 2018 - ACS Publications
Among all solid electrolytes, composite solid polymer electrolytes, comprised of polymer
matrix and ceramic fillers, garner great interest due to the enhancement of ionic conductivity …

Probing RNA conformations using a polymer–electrolyte solid-state nanopore

C Chau, F Marcuccio, D Soulias, MA Edwards… - ACS …, 2022 - ACS Publications
Nanopore systems have emerged as a leading platform for the analysis of biomolecular
complexes with single-molecule resolution. The conformation of biomolecules, such as …

AIE polymer micelle/vesicle photocatalysts combined with native enzymes for aerobic photobiocatalysis

N Zhang, S Trépout, H Chen, MH Li - Journal of the American …, 2022 - ACS Publications
Biocatalytic transformation has attracted increasing attention in the green synthesis of
chemicals due to the diversity of enzymes, their high catalytic activities and specificities, and …

A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer

MJ Whitley, DM Cardona, AL Lazarides… - Science translational …, 2016 - science.org
Local recurrence is a common cause of treatment failure for patients with solid tumors.
Intraoperative detection of microscopic residual cancer in the tumor bed could be used to …

Crowding induced collective hydration of biological macromolecules over extended distances

JT King, EJ Arthur, CL Brooks III… - Journal of the American …, 2014 - ACS Publications
Ultrafast two-dimensional infrared (2D-IR) spectroscopy reveals picosecond protein and
hydration dynamics of crowded hen egg white lysozyme (HEWL) labeled with a metal …

Effects of macromolecular crowding on the collapse of biopolymers

H Kang, PA Pincus, C Hyeon, D Thirumalai - Physical review letters, 2015 - APS
Experiments show that macromolecular crowding modestly reduces the size of intrinsically
disordered proteins even at a volume fraction (ϕ) similar to that in the cytosol, whereas DNA …

Revisiting molecular adsorption: unconventional uptake of polymer chains from solution into sub-nanoporous media

N Oe, N Hosono, T Uemura - Chemical science, 2021 - pubs.rsc.org
Adsorption of polymers from the solution phase has been extensively studied to cope with
many demands not only for separation technologies, but also for the development of …

Polyvinyl alcohol/sodium alginate hydrogels incorporated with silver nanoclusters via green tea extract for antibacterial applications

T Wang, F Zhang, R Zhao, C Wang, K Hu… - Designed monomers …, 2020 - Taylor & Francis
Silver-based nanoparticles and biomaterials have extensive biomedical applications owing
to their unique antimicrobial properties. Thus, green and facile synthesis of such materials is …