Respiratory pathogens represent a great burden for humanity and a potential source of new
pandemics, as illustrated by the recent emergence of coronavirus disease 2019 (COVID-19) …

Tuberculosis (TB) remains a global health problem despite almost universal efforts to
provide patients with highly effective chemotherapy, in part, because many infected …

In the past 2 decades, it has become increasingly clear that nonhuman primates, specifically
macaques, are useful models for human tuberculosis (TB). Several macaque species have …

While tuberculosis continues to afflict mankind, the immunological mechanisms underlying
TB disease development are still incompletely understood. Advanced preclinical models for …

Tuberculosis (TB) is a major global health problem and the only currently-licensed vaccine,
BCG, is inadequate. Many TB vaccine candidates are designed to be given as a boost to …

Despite the extensive research on CD4 T cells within the context of Mycobacterium
tuberculosis (Mtb) infections, few studies have focused on identifying and investigating the …

Ten million cases of tuberculosis (TB) were reported in 2018 with a further 1.5 million deaths
attributed to the disease. Improved vaccination strategies are urgently required to tackle the …

Among the animal models of tuberculosis (TB), the non‐human primates (NHPs), particularly
rhesus macaques (Macaca fascicularis) and cynomolgus macaques (Macaca mulatta) …

The composition of the microbiota in cynomolgus macaques is only partially characterized,
although this animal model is often used to study pathogenesis and preventive strategies …

Aerosol aerodynamic particle size is known to affect deposition patterns of inhaled aerosol
particles, as well as the virulence of inhaled bioaerosol particles. While a significant amount …