P Johnson, Q Zhou, DY Dao, YMD Lo - … reviews Gastroenterology & …, 2022 - nature.com
Hepatocellular carcinoma (HCC) is one of the most prevalent and lethal causes of cancer- related death worldwide. The treatment of HCC remains challenging and is largely …
A proactive approach to detecting cancer at an early stage can make treatments more effective, with fewer side effects and improved long-term survival. However, as detection …
A Jamshidi, MC Liu, EA Klein, O Venn, E Hubbell… - Cancer Cell, 2022 - cell.com
Summary In the Circulating Cell-free Genome Atlas (NCT02889978) substudy 1, we evaluate several approaches for a circulating cell-free DNA (cfDNA)-based multi-cancer …
VK Sarhadi, G Armengol - Biomolecules, 2022 - mdpi.com
Molecular cancer biomarkers are any measurable molecular indicator of risk of cancer, occurrence of cancer, or patient outcome. They may include germline or somatic genetic …
Over the past 10 years, circulating tumor cells (CTC) and circulating tumor DNA (ctDNA) have received enormous attention as new biomarkers and subjects of translational research …
EA Klein, D Richards, A Cohn, M Tummala… - Annals of …, 2021 - Elsevier
Background A multi-cancer early detection (MCED) test used to complement existing screening could increase the number of cancers detected through population screening …
M Ignatiadis, GW Sledge, SS Jeffrey - Nature reviews Clinical oncology, 2021 - nature.com
Historically, studies of disseminated tumour cells in bone marrow and circulating tumour cells in peripheral blood have provided crucial insights into cancer biology and the …
D Mathios, JS Johansen, S Cristiano, JE Medina… - Nature …, 2021 - nature.com
Non-invasive approaches for cell-free DNA (cfDNA) assessment provide an opportunity for cancer detection and intervention. Here, we use a machine learning model for detecting …
L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human health. As an emerging diagnostic technique, liquid biopsy can provide real-time …